Chapter 797

The visit process Yang Rui prepared for Jielikang and other companies was very short, but it was enough to let them know the work of the laboratory.

This is also a very important point. The experimental data of third rate laboratories are not credible, just like the articles of many unknown scholars in unknown universities, which are rarely cited. The main reason is the credibility problem. Scholars read these articles more to provide an idea. When they really need data, they will do it by themselves.

The data of deferonone in Huarui laboratory is very good, so Yang Rui asked them to understand Huarui laboratory first.

As for the specific data and so on, there is no need to release them.

What others see are simple data sets.

But these data sets are enough for the representatives of various companies to ponder for a long time.

At the end of the visit, Yang Rui, together with grace, Wei zhenxue, Wang Xiaoyun and other members of the pharmaceutical group, kindly sent the representatives of the companies out of the door.

Watching the cars start and then slowly leave, grace laughs.

Wei zhenxue looked at Grace's smile inexplicably and asked, "do you like watching car exhaust, too?"

Wang Xiaoyun habitually helped Wei zhenxue translate.

Grace did not understand the frown: "also?"

Wei zhenxue could understand the words. "Oh," he said with a smile, "I don't mean I like watching car exhaust. I don't like watching car exhaust, but Bao Si likes it. Have you heard the story of the warlords in the war drama? There is a woman who likes to watch fireworks and the Great Wall... "

"Old Wei." Yang Rui was stunned and sighed: "how can you make people come here?"

Wang Xiaoyun was also silly. She stopped translating later and said, "Lao Wei, fortunately you don't know English, otherwise you can smoke in the afternoon."

"What do you mean?" Wei zhenxue doesn't understand.

"Cremate your cigarette." Wang Xiaoyun is fierce in voice and color.

Wei zhenxue was not affected at all. He said with a smile, "impossible. Our hometown rules, people die first stop seven days, I die today, you burn me today? You are too bad. Fortunately, you are not my daughter-in-law. "

Wang Xiaoyun said: "I am bad? You don't want to ask, "Why are you dead?"

"There's no need. We're not afraid of death. Don't go to the chemistry department, do you?" Wei zhenxue made a resolute expression, with the facial features on the big face, just like the death squads of the puppet army.

Grace looked blankly at the two people who spoke fast and asked Yang Rui in surprise, "they were talking to me just now, right?"

"Yes."

"Why don't you say half of it?"

"Well..." Yang Rui didn't know how to explain the story of a normal person who was angry with him.

"What did I do wrong?" Grace thought Yang Rui's expression was very familiar. She said, "I always make people angry. It doesn't matter. Just tell me what's wrong."

"It's not your problem." Yang Rui was too lazy to explain. He said directly, "you just watched the people of Jericho leave and laughed. Why?"

"I wonder how they will come back after they have evaluated the prospect of deferoxane." Grace had a soft smile again.

"The profit of deferoxane will not be too high. After all, deferoxamine exists."

"For drugs that have just undergone animal experiments, the most important thing is how well they can pass clinical trials." Grace said, "I hope you can choose the right company to sell it, not the one with the highest price."

"Yes?"

"While the companies that offer the highest prices may be the ones that are most interested, it does not mean that they have the strongest executive power." Grace said: "it may take only two or three years for a suitable enterprise to complete the clinical trial of desferridone. For an unsuitable enterprise, it may take seven or eight years..."

"I understand that I will choose the most suitable enterprise, even if it doesn't make money." Yang Ruiyi's right words.

"It's impossible not to make money." Grace glanced at him and said, "I'm the only pharmaceutical chemist in your team. I don't need any salary. The total development time is no more than three months. Even if you add in your theoretical research time, it doesn't cost much. You will become a millionaire."

"That's good, too." Yang Rui laughs.

……

the second day.

Valentine also issued a similar cry of surprise: "the Chinese are really getting rich."

Arnold is also calm face: "54 points, is really a rich score."What they do is the evaluation of clinical drug candidates, which is to evaluate the probability of a drug passing clinical trials.

Only through the drugs with high probability can they enter the clinical candidates, and then have the opportunity to carry out clinical trials.

Different from ordinary people's intuition, those drugs that may be very effective in the treatment of diseases do not have a strong advantage in the evaluation of clinical candidate drugs. The reason is very simple. There are many good drugs. You need to pass the examination to make money. What you can't pass is just a rainbow.

Any drug with high scores in the evaluation of clinical candidate drugs means that it has a bright future. Companies like jericham and Pfizer like to buy drugs after the animal experiment stage.

They will spend tens of millions of yuan to buy a drug, and then spend two or three times the price for clinical trials. Once they pass the clinical trials, they will be able to earn back all their previous efforts.

It is also for this reason that three-quarters of the original drugs developed every year around the world are developed on the targets of existing drugs.

This kind of original medicine, although also original, but the degree of original is not high, but very safe.

They are cash cows that can safely make a profit.

An extreme example is the antidepressant SSRIs. FDA has approved no less than seven products, each of which has more than $1 billion in sales.

In any pharmaceutical company, the "blockbuster" is an important capital, which can be met but not sought. In contrast, it is much easier to make an original drug by targeting SSRIs.

Deferrone is different, because the last seven active substances left by Yang Rui have good effect, and their scores are very high, which greatly increases the probability of deferrone passing clinical trials.

As long as it can pass the clinical trial and go on the market, how to sell it is another matter.

According to the evaluation model of Jielikang, compounds with a score of more than 30 can be included in the list of clinical drug candidates. Compounds with a score of more than 40 are basically in the forefront. There is no big problem, so clinical trials will be carried out.

As for drugs with a score of more than 50, there are not necessarily a few every year.

Arnold also calculated and calculated, and then determined that deferrone reached the standard of 54 points.

"This guy's got a lot of patents." Arnold didn't know whether he was admiring or angry.

If there's a chance, big pharmaceutical companies don't mind plundering small companies by grabbing patents.

For a drug with an annual sales volume of hundreds of millions and its own value of more than one billion or even ten billion, large pharmaceutical companies can do anything.

Frankie checked the patent himself and said, "Yang Rui is still suing for PCR. He must be very concerned about the patent."

"Patent of intermediates, patent of preparation methods, patent of products, patent of crystal, patent of amorphous form and patent of composition are registered at one go!" Arnold bared his teeth and said, "he's too insecure to give people more trust."

Frankie pondered the question of "trust" for a long time.

……