Chapter 796

Arnold and Frankie discussed with their heads down, and the staff from other companies also discussed and calculated in a low voice.

After reading what she had in her hand, grace looked up and saw that several people were talking in the corner. She could not help but curl her lips and said, "you are all doing the evaluation of clinical candidates. The evaluation of each family is not much different. Why don't you read it out loud, save some time and let everyone put their energy into the real research."

We are all people from pharmaceutical companies. We all know what we are doing with our chin. But there is a big difference between a fig leaf and no fig leaf. It's like your neighbor has a baby. No matter it's your neighbor's or your own, you don't have to say it - "Congratulations, "The child is really yours" doesn't make the neighbors happy.

Unfortunately, grace is not a good neighbor. No matter other people are still looking at each other, she said to herself: "the animal experiment results of desferridone are very good. You can see what's the use of your secret calculation. Can Huarui company not know what it has done?"

"The results are really very good, but the side effects are also very serious. We were just discussing the side effects." Arnold lied and came.

Grace snorted, "it's just gastrointestinal reactions, joint pain, mild drug allergies, liver dysfunction, zinc deficiency, weight gain, dry skin, rashes, agranulocytosis and neutropenia... What's the big deal? Compared with the risk of thalassemia, these are just simple problems."

Yang Rui stared, but added: "these adverse reactions are relatively mild and reversible, which are related to the dose and individual sensitivity. The most serious complication is agranulocytosis, but the probability of occurrence is very low, and it is temporary."

"Even so, would agencies like FDA think so? There are so many problems in animal experiments. It takes a long time to enter clinical trials. " So far, no company has proposed a plan of acquisition or purchase, but at this stage, Arnold and others have consciously lowered their expectations of deferoxane.

Business in the pharmaceutical field is very expensive. It's not easy to reduce any price. Arnold himself is a professional in charge of negotiation in the company, so he won't let go of a word.

Grace scoffed at Arnold's words and said: "deferoxane can be used orally. This alone makes it a great improvement over deferoxamine. FDA will understand if they still play golf..."

"Or the Yankees VIP box, the same effect." The man sitting on the right said a word, followed by another: "our favorite American is always baseball, always baseball!"

"Because your football is so boring." Frankie uses the word football. In England, football is football, while in America, it is rugby. Any Englishman who is unhappy with the Americans, or any American who is unhappy with the British, can use football to provoke and try bailing.

The man on the right felt the provocation, sneered and said, "if I feel bored, I will find a woman instead of a gun."

"You're Raymond from greenstone corner, aren't you?" Yang Rui didn't want several foreigners to quarrel in the conference room of Peking University. He stood in the middle and interrupted them.

"I'm Raymond. You have a good memory." Raymond has broad shoulders and a strong voice.

"Greenstone corner is also an original pharmaceutical company, and I certainly remember that." Yang Rui smiles and nods. Compared with the well-known super pharmaceutical companies like Pfizer, greenstone corner is only a medium-sized original pharmaceutical company. Nevertheless, its annual sales are more than $2 billion, and it is also a giant in other industries.

Yang Rui looked at the two sides and said with a smile: "we are here to understand the animal experiment of deferonone. Let's talk about animal experiments today. I'll talk about the rest later. "

"Animal experiments are perfect. There's nothing to talk about." Grace holds her chest in both hands and looks at a group of men with pride. She is short of a "local chicken and dog" evaluation.

"You do have beautiful data, but we don't have all of them." The Norwegian sitting on the far right looked up and said, but his eyes were on grace.

Grace's Nordic blood is very eye-catching, and it is incomparably in line with the Norwegian aesthetic. They say no, in fact, they prefer this kind of fashionable girl mixed with Nordic and British American styles.

Grace turned a blind eye to his eyes and said, "you don't need all the data. The results are enough for you to evaluate."

Arnold coughed hard and was reluctant to talk about the assessment again.

Representatives of other companies are silent, looking down at the experimental instructions Yang Rui gave them, quietly doing their own evaluation.There was a sudden silence in the conference room.

Grace snorted discontentedly, sat down next to Yang Rui and said, "you should give me the enhanced version of the information now."

"I couldn't have taken that data out of the lab." Yang Rui said, "I'll show you when I get back."

"Look at them, they can't finish the analysis in an hour or two." Grace said, "you should find a good salesman. Otherwise, you can't get a good price for deferonone."

"How do you know I'm going to sell deltamethrin? I can do clinical trials myself. "

"Ready for 200 million dollars?" Grace gave Yang Rui a silly look.

1984 The $200 million in 2008 is not a small number, at least equivalent to $400 million in 30 years. In fact, after 30 years, pharmaceutical companies often make more than $700 million for a new drug. It's not that we have to spend so much money, but if we don't have so much money, the risk of closing down because of money will be greatly increased, and investors will lose confidence.

Yang Rui doesn't have US $700 million, and he can't get us $200 million. Therefore, if deferonone wants to go public, it can only be done through large companies.

Yang Rui laughs two times, saying he does not believe the words: "we can be listed in other countries."

"It's just more money. The United States will not reduce the number and cost of your clinical trials just because your drugs are on the market in other countries, nor will Europe. Only drugs that have passed the FDA can enter the European and Asian markets through various agreements. " Grace focuses on explaining to Yang Rui that she doesn't want a good drug to go on the market because of Yang Rui.

Yang Rui sighs. This is the strength of American Dad. If you don't follow his standard, you will have to spend more money. This is more terrible than death penalty.

There is a business of beheading in the world. There is no business of losing money.

But from another point of view, although the bloated and corrupt FDA is inefficient, the safety of the drugs approved by FDA is indeed commendable. Compared with the drug administration of the third world countries, FDA is still more reliable.

"If jerichon offers, don't be less than $20 million." Grace said: "after the completion of the animal experiment, deferonone should be able to sell at this price."

Yang Rui said with a simple smile, not talking about the price.

Grace thought he didn't want to sell it, and said, "you can sell it to large pharmaceutical companies as soon as possible, so that patients suffering from thalassemia can get life-saving drugs. If you want to make money, I suggest you set up a non-profit charity fund. Of course, you can continue to invest in laboratory research. "

"You'll leave then." Yang Rui asked.

Grace nodded naturally and said: "although I plan to stay in China for five years, deferoxane has exceeded the expected progress, which makes me have no reason to stay. The time saved is for the promotion of deferoxane. In addition, I plan to raise part of the funds to fund Mediterranean anemia patients who can not afford treatment."

"Ideal."

"Thank you." When she was a student, grace established the idea of working for a lifetime in a non-profit organization. After her doctoral degree, she even refused a number of high paid jobs. She traveled to and from Africa and other places to do research on genetic diseases that few pharmaceutical companies paid attention to. Finally, she established the research direction of metal chelators, which is difficult to make money.

If we want to find a reasonable analysis, grace may have too much "white guilt", working in Africa, helping poor African families, alleviating the pain of African children caused by genetic diseases, and making grace feel more relaxed.

Yang Rui didn't comment on this. He waited for the representatives of Jielikang and other companies to read the documents. He said: "the animal experiment on deferrone in Huarui laboratory is coming to an end. We welcome representatives from various companies to come to the company to learn about the specific situation. Each company is limited to two people. Those who are interested can fill in the application later."

"Give me an application."

"We want it, too."

"It's all done." Arnold laughed twice and said, "Jericho is not afraid of competition."

Yang Rui nodded and asked people to send us the application.

Arnold whispered to Frankie, "check their patent applications."

……