Chapter 144

The light make-up of Yao Yue's fresh and sweet smile gives Yang Rui a little surprise.

Yang Rui has always been unable to see whether a woman's make-up is good or not. Except for the night club style heavy make-up, he, like most men, will not study the details of a woman's face to know whether it looks good or not. That's how girls make up.

However, girls in the 1980s obviously didn't understand this. Just two years ago, "Iron Lady" was still being publicized all over the country. The so-called "treating women as men and men as livestock" was absolutely commendatory. Before the 1980s, the Royal scholars wrote a lot of Hua Mulan style reportage that "who says women are inferior to men".

With the reform and opening up, women's aesthetics began to awaken. Handmade sweater, flower shirt, red skirt, bell bottoms and trousers gradually appeared, but few people still make up their makeup. Especially in the prefecture and county, they usually use some clam shell oil to make some cream, even if they have been dressed up.

Yao Yue is a girl from a big city. Although she has poor conditions, she is invincible in youth after all. After dressing up carefully, she can easily highlight her bright and lovely image as a girl.

For Yang Rui, who hasn't seen a TV movie for a long time or even a fashion poster for several months, the impact of real 3D girls is far stronger than that of 2D girls.

More unbearable than Yang Rui is He Cheng, an experimental assistant.

Growing up in a town, he Cheng's activity space is only around Xibao Town, and his only chance to see beautiful women is movies.

However, the hazy town film film, where can be compared with the living beauty.

He Cheng looks at Yao Yue's lower leg under her long skirt, and he has the impulse to have nosebleed. The experiment he is doing on his hand is completely out of order.

"Beautiful Yang Rui naturally praised.

In terms of appearance, he is somewhat confident.

First of all, it was Yao Yue who blushed. He bowed his head and said, "yesterday's clothes were dirty."

The answer is a little puzzling, I don't know what to explain.

In fact, Yao Yue felt that she was a little too ostentatious.

The red one-piece dress under the white coat is as bright as a catwalk in the world of green military uniform and grey cloth clothes.

As far as the sense of the times is concerned, it is equivalent to a certain star wearing the dress when shopping on the shanseri Avenue in Paris, walking like a five mile shop in tangjiapu.

But Yao Yue is also telling the truth. When Yao Yue came to Xibao Town, she brought such a change of clothes. As for why she wanted to bring her most beautiful clothes, which she bought from Shanghai, this kind of little girl's mood is not enough.

Yang Rui thought it was very good-looking and in line with his own aesthetic standards. He naturally looked around her and said with a smile, "what can I do? It's wasteful to wear a white coat outside, and it's easy to get dirty if you don't wear a white coat. "

"When my clothes are dry, I'll change them back." Yao Yue obviously did not get such a direct praise. He was more shy when he was happy.

Luzhi nudged him and said, "what do you want to do when you come back? You don't stay in the laboratory all day. You still have to wear your own clothes when you go out."

"Don't talk about clothes. What are you doing? What can I do for you? " Yao Yue is sorry to go on.

Yang Rui had no experience in love, and he failed to seize the opportunity to pursue fiercely. He was biased and said, "we are doing verification experiments to test the authenticity of several Japanese papers."

When Yao Yue saw what he had said about the experiment, she immediately felt a lot more relaxed. Seeing he Cheng's preparation for the experiment, she picked it up and looked at it, and said, "did you tell me about plant extraction?"

"Yes, Japan's territory is small, and animal husbandry has never been competitive. Therefore, their scientific community has always disliked tissue extraction. For the sake of their interests, pharmaceutical companies are actively trying plant extraction while developing tissue extraction. Microbial culture and chemical synthesis have all made some progress." Yang Rui gave a general explanation. In the field of biopharmaceuticals, Japan has seized the opportunity and developed rapidly. Some biological products, such as insulin, occupy the global market. The same is true of coenzyme Q10. Japan was the first to make efforts in this field, and tried plant extraction, microbial culture and chemical synthesis. In the 1980s, it selected semi plant extraction and semi chemical synthesis, and in the 1990s, it gradually implemented microbial culture. The money spent was gold mountain and silver sea. In this regard, China in the 1980s could not afford admission tickets.

However, the high cost of biopharmaceuticals lies in R & D. for Yang Rui, who already has the answer, a successful replication is not so expensive.

Of course, it's relatively inexpensive. His lab has spent more than 30000 US dollars, plus 20000 US dollars in cash. This time, it's a chance to make one or two attempts. If it fails, many of the investments will not be recovered.It's still Yang Rui's good luck to catch up with the last bus of plant extraction method. If it's microbial culture method, you don't have to try it. A good fermentor can sell for tens of thousands of dollars, and a string of fermentors will cost hundreds of thousands of dollars. Yang Rui's dividend this year is not enough to copy it once.

As for the most advanced and the lowest cost pure chemical synthesis method, until 2014, there was no mature industrial production mode. Large international pharmaceutical companies invested tens of millions of dollars in this, which is an invisible bottomless hole.

Although they started to help in the laboratory, they didn't know about R & D itself. Yao Yue looked at it for a while and then asked curiously, "has Japan made achievements? Shall we do research on localization? "

On the contrary, Yang Rui wondered, "why must Japan have achieved something before we copy it?"

"Localization is different from copying." Yao Yue was anxious: "that is to fill the gap in China and save foreign exchange for the country..."

"That's not copying. What kind of localization research is the most time-consuming and capital wasting project, which is not military equipment. " Yang Rui said in his heart: even if I plagiarize, I will not copy the patented technology. What's the meaning of doing repetitive research.

Lu Zhi also looked at the preparation of the experiment with her head sideways. She was not sure what experiment Yang Rui was going to do. She asked, "do you want to do the experiment on the basis of Japanese research? It's more difficult. "

In the minds of Chinese people, foreign research is naturally advanced, and it is extremely difficult to do research on the basis of foreign countries.

There is no mistake.

Experimental science depends on experimental equipment. Without experimental equipment, experimental science is rootless. Perhaps, occasionally, one or two ideas come out to replace repeated machinery and equipment. However, if you want to spend your whole life relying on these ideas, this kind of people should not engage in experimental science, they should sing little stars.

Foreign laboratory equipment is advanced, they can study a wide range. If we want to do research on the basis of them in China, we'd better have more advanced equipment. At worst, we have to have similar equipment.

For example, the gatekeeper, levinhock, a Dutchman with no formal education, grinds out an excellent lens and sees the world of microorganisms. Even if his article "levinhock uses a homemade microscope to observe the dry records of skin, meat, bees and other insects" is so rough, scientists from the Royal Society of England, The paper had to be published in the Journal of the Royal Society of England after it was confirmed by levinhock's microscope.

No matter how clever other people are, no matter how beautiful they sing, and no microscope with a magnification of two or three hundred, he is not qualified to do research on the basis of levinhock.

With the development of modern industry, the threshold of science has become higher rather than lower. Catching up with the developed countries is a hard and even hopeless task for the Chinese people in the 1980s.

If Luzhi had worked in a university laboratory for three or four years, he would not have asked such a question.

However, Yang Rui's answer is yes: "we have to avoid the technical barriers of Japanese pharmaceutical companies. Well, we can't call them barriers now, they are just stumbling blocks. Anyway, we have to complete some basic research in our own way, which is the basis of plant extraction method. Then, we have to build on this basis, Establish their own plant extraction method of technical barriers. The work is very heavy and there are few researchers, so let's start now. "

Yang Rui said, and set up the task.

If it were a large pharmaceutical company in Europe and America, it would not do so. They will first use the research results of Japanese pharmaceutical companies, no matter whether they have technology patents or not, and then, after the invention of profitable technologies based on these patents, they will reverse their search for solutions, which will naturally be very good and make money happily. If you really can't find a solution, you will infringe the law. When the other party sues, you will send dozens of lawyers to accompany the other party to fight a lawsuit every day. At the same time, you will sell medicine happily.

Small and medium-sized pharmaceutical companies are afraid of this large vulture. Because this kind of patent lawsuit often lasts for several years. The lawyers with dozens or hundreds of people may spend tens of millions of dollars a year. Small and medium-sized pharmaceutical companies are going to close down before the court decides. Only large pharmaceutical companies can afford it.

Yang Rui is not a pure researcher. If he wants to make money through this technology, and he has only a very small biological R & D team, he must first solve each other's technology patents, then establish his own technology patents, and then ask for all the patents.

All these steps and processes are supported by experiments and papers.

If there is no process, take a result. Except for the Super Big Mac, the drug administration of any country will not pay attention to it. Pharmaceutical companies will not make good bids.

Even if it's just a kind of extraction method, we have to establish a strict R & D chain.This is a huge test for Yang Rui, who is seriously short of funds. He can only comfort himself. Fortunately, it is the era of biotechnology.

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