Chapter 495： : The minecart was robbed and arrived at Bosbon

[This chapter is the third chapter]

I know that there is a software developer conference, have you heard of a biological developer conference? Since yesterday, the world's first biodeveloper conference was held in Shanghai.

The theme of this year's conference is "Link Opening", which aims to promote the linkage of various communities in the entire engineering biology industry, cultivate a better ecological environment, promote the development of biotechnology products, and open a new link in the engineering biology ecosystem. Experts gathered at the conference, as well as representatives from over a hundred companies and many investors.

Using DNA as the code, professional biological developers are here

Synthetic biology is a new cross-science in the 21st century. It can use Escherichia coli to produce bulk chemical materials and get rid of the constraints of petroleum raw materials. Yeast produces artemisinic acid and rare ginsenosides to reduce costs and promote the development of new drugs; engineering bacteria do not "Injury" normal cells and specifically attack cancer cells...

"In the era of'convergence', the research and development capabilities of life sciences and biotechnology are in urgent need of improvement." Academician Zhao Guoping of the Chinese Academy of Sciences said at the conference. Synthetic biology uses the “bottom-up” concept of engineering to break the boundaries between “natural” and “unnatural”, from systematically characterizing natural biological macromolecules with functions such as catalytic regulation, making them standardized “elements”, to Create new biological components such as "modules" and "circuits" and cell "chasses" to build artificial life systems with various uses.

Just as there are software engineers who write codes in the IT industry, biological developers are people who use DNA as the "code" and focus on the innovation of the source of biotechnology and the development of new products. The initiator of the conference, Guo Haotian, the founder of Red Panda Bio (Shenzhen Xunzhu Biotechnology Co., Ltd.), said that in recent years, the division of labor in the biotechnology industry has become more and more detailed, and an intermediate group has appeared in the chain of the biotechnology industry. It does not study basic mechanisms, nor is it engaged in clinical trials or scale-up production, but specializes in the development of strains of fermented products, the reconstruction of chassis microorganisms, the design of protein drugs, and even molecular breeding and organoid transformation. The industry refers to this group of people as biological developers.

Provided by Wenhui, the picture point "sugar" becomes gold, and biological development has many magical uses

What's the use of biological developers? Zhao Xinyan, Chairman of Finca Technology, cited the rapid growth of the perfume industry in recent years as an example. Sandalwood is a precious fragrance extracted from the sandalwood tree. The price of sandalwood can reach 2,000 US dollars per kilogram. A technology of biosynthesis of sandalwood from sugar can reduce the price to 2,000 yuan per kilogram. In addition to lowering prices, biosynthetic technology can also greatly reduce the plant cultivation cycle and improve safety. A kind of spice extract that needs to be planted in 150,000 mu of flower fields for one year, using a biosynthetic method, only needs to be synthesized in a petri dish for 5 days to obtain.

Fenkai Technology is researching the method of artificially synthesizing the "king of spices"-Ambergris, which is a fixative with "subtle velvety softness". Zhao Xinyan said that if there is no such substance in the perfume, the fragrance will stay for up to 40 minutes, and the fragrance will stay for more than 4 hours if added. Therefore, almost all high-end perfumes are added with ambre.

At present, the company has completed the mass production of sclareol-sclareolide, and it is urgently needed to develop the next step of synthesis technology.

The conference also held a sustainable development challenge, that is, by providing a variety of biological solutions to release biological potential to promote the sustainable development of various fields. Teams from Tsinghua University, East China University of Science and Technology, Jiangnan University, ShanghaiTech University and other universities participated in the on-site competition.

Provide basic "computing power" for life sciences

Just like IT workers need computing power, biological developers also need high-throughput, low-cost "development tools". The emergence of the ultra-high-throughput carrier test platform Red Panda has solved the troubles of many biological developers.

"We have encountered many such scenarios in the past. On the one hand, developers working in the front line of the laboratory did not realize that there are already good tools on the market to help them speed up research and development, reduce costs, and reduce repetitive labor; on the other hand, On the one hand, it is difficult for organizations with platform capabilities to reach customers, and they often need to spend a lot of cost to promote.” Guo Haotian said that Red Panda Bio can provide a cloud laboratory service for million-level protein recombination, which is better than international general tools. It is 6 orders of magnitude higher, and the cost is only one percent of that of ordinary tools.

The reason for achieving such a "cost-effective ratio" stems from the fact that Red Panda Biology is based on synthetic biology cell programming technology. This is a brand new experimental method. Simply put, it is to provide bacteria with a piece of DNA code so that they can be in the cell. Work autonomously.

As a Shenzhen startup, why come to Shanghai for a meeting? Guo Haotian admitted frankly that he has taken a fancy to Shanghai and the Yangtze River Delta's high-quality biomedical resources. As a "basic computing power" in life sciences, this tool can be linked to almost all biological industries and provide high-quality services for them.

"Ukawa Floating" talked about several points, but there was a problem with the connection. If we look at it from the perspective of the protagonist, what can we see? The protagonist returned to his hometown because he didn't have much time. Pneumoconiosis is an embarrassing disease. For many people in China, this is undoubtedly sentenced to death. After the protagonist with a painful illness returns to his hometown, what kind of life test he has to face, in the face of all kinds of hardships, how to show his feelings after illness, this is the first core theme that the author wants to tell everyone , Caring for pneumoconiosis, or starting to pay attention to a certain group that has been neglected.

When the protagonist returns to his hometown, his mother’s experience is lingering like a nightmare. The only thing that can comfort his soul is to do something silently, to erect a monument for his mother, and silently do whatever he can think of. . This is a kind of repentance for the mother's long-standing debt.

For his own brother, no matter what happened before, the first thing he thought of when he was still alive was reconciliation, reconciliation with his brother, excuses from his past, and bid farewell to his future. And meet your enemies. The scene with red eyes did not happen, and he even stopped all those who wanted to help. The stimulating scene was replaced by plainness, and everything was over. What is the point of mentioning these grievances for a dying person?

The second core point lies in the relationship between people. The protagonist’s wife divorced himself, the protagonist’s brother is at odds with him, and friends are still friends, but they all have their own lives. Even if they are enemies, the protagonist does not. Willing to look at all this with a vengeful eye, life is still going on, everyone is going on, but many people who have had intersections with them before, have lost contact at this moment, no one wants to mention the past, and no one Willing to go completely out of a certain thing. Therefore, everything becomes very awkward, and the protagonist wants to find something out of it, but in the end finds nowhere to start.

The origin of Thousand Island Lake and the influence of the changes of the times on people appear in this film imperceptibly, but this imperceptibility has not become the driving force leading the film forward. Most of the time, there is not much intersection between these elements and the film. ,This is where the problem lies. Many times we have expectations. Our expectations for a film, especially a literary film, require the creator to express it. The expression of this film is divided into several aspects, but these several aspects are single independent individuals. How these independent individuals are well connected through the protagonist, the tragic character, is the key to testing the creator’s original intention. If you can't handle this well, then no matter how good a film is, it will at best become an independent segment, but the film needs to be coherent.

In addition to self-expression, how many core domestic literary films have?

2021-10-1009:27 People's Information of the Pearl

The second core point lies in the relationship between people. The protagonist’s wife divorced himself, the protagonist’s brother is at odds with him, and friends are still friends, but they all have their own lives. Even if they are enemies, the protagonist does not. Willing to look at all this with a vengeful eye, life is still going on, everyone is going on, but many people who have had intersections with them before, have lost contact at this moment, no one wants to mention the past, and no one Willing to go completely out of a certain thing. Therefore, everything becomes very awkward, and the protagonist wants to find something out of it, but in the end finds nowhere to start.

The origin of Thousand Island Lake and the influence of the changes of the times on people appear in this film imperceptibly, but this imperceptibility has not become the driving force leading the film forward. Most of the time, there is not much intersection between these elements and the film. ,This is where the problem lies. Many times we have expectations. Our expectations for a film, especially a literary film, require the creator to express it. The expression of this film is divided into several aspects, but these several aspects are single independent individuals. How these independent individuals are well connected through the protagonist, the tragic character, is the key to testing the creator’s original intention. If you can't handle this well, then no matter how good a film is, it will at best become an independent segment, but the film needs to be coherent.

Domestic literary film directors are very accustomed to self-expression, but they always ignore the continuity of the story. Even the obscure and sophisticated literary films should have a theme to connect, otherwise no matter how good the clips are, they can only be fragments, exquisite. The five senses lack a thread, which is embarrassing.

Is "Sugar-Free" really sugar-free?

According to the test, all milk teas called "sugar-free" were found to contain sugar, even higher than some samples with normal sweetness.

According to a test conducted by the Shanghai Consumer Rights Protection Committee, among 27 milk tea samples with normal sweetness, the sugar content was 11-62 g/cup, and the average sugar content was 34 g per cup, with the highest milk tea. The sugar content is equivalent to 14 cubes of sugar.

Among the so-called "less sugar", "low sugar", "de-sugar" or "sugar-free" milk teas, all 20 of them have sugars measured, with an average sugar content of 2.4g/100ml, and a minimum of 1.2g/100ml.

"Healthy China Action (2019-2030 advocates that the average daily added sugar intake per capita is no more than 25 grams. Other countries have similar suggestions:

TheAmericanHeart;suggeststhatmenconsumenomorethan150calories(about9teaspoonsor36grams)ofaddedsugarperday.Forwomen,thenumberislower:6teaspoons(25gramsor100calories)perday.

The American Heart Association recommends that men consume no more than 150 calories of added sugar per day (about 9 teaspoons or 36 grams). For women, this number is even lower: 6 teaspoons (25 grams or 100 calories) per day.

Too much sugar is very harmful to the body. In a 2014 study published in the Journal of Internal Medicine of the American Medical Association, there was an association between a high-sugar diet and a high risk of heart disease.

Overthe course of the 15-year study, people who got 17% to 21% of their calories from added sugar hada 38% higher risk of dying from; disease compared with those who consumed 8% of their calories as added sugar.

A 15-year study showed that 17%-21% of the calories consumed came from people with added sugar, and their risk of dying from heart disease was nearly four times higher than those with 8% of calories coming from added sugar. become.

Is there really milk in milk tea?

Although there is only one word for milk tea and milk, the milk in some milk teas is not milk, but instead of non-dairy creamer or creamer.

Research shows that in a test of protein in milk tea, the protein content is low, while the trans fatty acid content is high.

In this regard, experts believe that because the indicators of protein and trans fatty acids are out of balance, it means that the business may not use "real materials", and the raw materials of milk are likely to be replaced by products such as creamer.

But what are trans fatty acids?

Artificialtransfats(ortransfattyacids)arecreatedinanindustrialprocessthataddshydrogentoliquidvegetableoilstomakethemmoresolid.Theprimarydietarysourcefortransfatsinprocessedfoodis "partiallyhydrogenatedoils."

Artificial trans fat (or trans fatty acid) is produced in an industrial process. Hydrogen is added to liquid vegetable oil to make it more solid. The main dietary source of trans fats in processed foods is "partially hydrogenated oil."

Trans fatty acids are commonly used in foods such as cakes, biscuits, quick-frozen pizzas, French fries, and popcorn.

The Dietary Guidelines for Chinese Residents recommends that the daily intake of trans fatty acids should not exceed 2 grams. After testing the milk tea samples, it was found that the amount of trans fat in a cup of milk tea exceeded the human body's intake for three days.

Trans fatty acids are as harmful to the human body as sugar.

Transfatsraiseyourbad(LDL)cholesterollevelsandloweryourgood(HDL)cholesterollevels.Eatingtransfatsincreasesyourriskofdevelopingheartdiseaseandstroke.It’salsoassociatedwithahigherriskofdevelopingtype2diabetes.

Trans fats will increase your bad cholesterol levels and lower your good cholesterol levels. The consumption of trans fats not only increases the risk of heart disease and stroke, but also increases the risk of type 2 diabetes.

A cup of milk tea = 8 cans of Red Bull? !

Have you ever tried a situation where you can’t sleep after drinking milk tea at night?

That is because milk tea generally contains a large amount of caffeine, and the content exceeds the limit several times.

In a test, experts tested 51 samples and found that the average caffeine content of the samples was as high as 270mg/L, and the highest was 828mg/L.

Research shows that a cup of American coffee (medium cup) has a caffeine content of 108mg, and a can of Red Bull beverage has a caffeine content of 50mg. In comparison, the caffeine content of some milk teas is terribly high, one cup of milk tea = 4 cups of coffee! = 8 cans of Red Bull!

Experts pointed out that caffeine is generally present in beverages such as coffee and strong tea, and the single intake of healthy adults should not exceed 200mg. People such as pregnant women and children should not take caffeine, otherwise it will cause anxiety-like symptoms, such as palpitations, tremors, and sleep disturbances.

The dangers of excessive caffeine intake are not only that.

Caffeine;thecentralnervoussystem,releasesfreefattyacidsfromadipose(fatty)tissueandaffectsthekidneys,increasing,whichcanleadto

Caffeine stimulates the central nervous system, releases free fatty acids from adipose tissue, affects the kidneys, increases urination, and causes dehydration.

What’s shocking is that most milk tea shops don’t have any reminders about the caffeine in milk tea.

After reading these research data, is the milk tea still fragrant in your hands?

While China's financial technology is booming, it also brings new challenges to regulation. The Governor of the People's Bank of China Yi Gang recently emphasized that an appropriate firewall should be established to avoid the spread of financial risks across departments and industries. Disconnect the improper connection between financial information and commercial information, and prevent the closed-loop effect of "data-network effect-financial business" from creating monopoly.

China's financial technology continues to develop and innovate, reducing the cost of financial services, improving the efficiency of financial services, and effectively helping inclusive finance.

"Driven by large technology companies, China's mobile payment has developed rapidly, and the current penetration rate has reached 86%." Yi Gang recently introduced at the Bank for International Settlements (BIS) International Conference on Supervision of Large Technology Companies, China's mobile payment and online payment rates Both are not more than 0.6%. UUreading users can also enjoy customized financial products when using electronic payment tools to collect payments. In addition, with the empowerment of digital technology, the entire process of credit approval and risk control can be digitized and online, reducing reliance on collateral, and better satisfying the "small, frequent and urgent" financing of small and micro enterprises need.

The picture shows consumers scanning QR codes in a convenient market in Handan City, Hebei Province. Photo by Xinhua News Agency reporter Wang Xiao

However, in Yi Gang's view, the continuous development of financial technology has also brought new challenges to regulation. Some platform companies engage in unlicensed or out-of-scope financial services and provide financial services such as wealth management, credit, and insurance under the same platform, which magnifies the possibility of cross-product and cross-market contagion of financial risks. Some platform companies have violated regulations in their payment business, and they have invested in various types of financial assets in violation of the provisions deposited by customers. Some platform companies have nested credit services such as "huabei" and "borrowing" in the payment link, misleading consumers . Some platform companies conduct unfair competition through monopolistic positions, and they excessively collect or even abuse consumer information, threatening personal privacy and information security.

"Finance, as a franchise industry, must be licensed to operate." Yi Gang said that in order to cope with challenges, China has continued to make up for the "shortcomings" of the regulatory system and has successively introduced measures to promote the healthy and sustainable development of the platform economy.

Yi Gang said that in the next step, it will continue to strengthen the supervision of the payment field. Implement the supervision of financial holding companies.

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