Chapter 186

Chapter 186 methyl ethyl ketone inhibitors

Although he has been stabbed several times, Qi Hong is still energetic. He directly refuses Liang Shaoming's suggestion to continue to recuperate and observe. He and Chen Qun follow Huang Haitao and rush to the laboratory together.

As the toxin was determined, other requirements were reduced a lot. Although the first level emergency response of the hospital was not lifted, all medical staff were not so worried.

After all, any unknown toxin or virus is the most dangerous. What we already know is not so terrible. Because there are mature solutions.

When Chen Qun and Chen Qun came to the laboratory, they saw that several colleagues were busy in the room, carrying zebrafish as the living experimental vector, and carrying out the targeted pathological verification of the mutant gene.

Several boys saw that Huang Haitao looked much better. They immediately welcomed him and reported on his progress. They even forgot to inquire about Huang Haitao's illness.

"Mr. Huang, after we determined the toxin, we contacted the records of gold poisoning and cesium poisoning to speculate that the gene mutation now appears, leading to respiratory failure. It mainly produces an enzyme called kinase, which leads to excessive proliferation and growth of human cells and produces a large amount of effusion. "

"At the same time, gold and sodium sulfide will lead to a decline in the ability of the human immune system, stimulate the swelling of the lymphatic system, block the respiratory tract, and the pathological changes caused by kinase, making the disease very serious. However, there are also successful treatment schemes abroad. What we need to do now is to find out a suitable drug to suit the case. "

Huang Haitao frowned slightly, "for those who don't know much about genetics, can you tell me simply what the correct coping plan is?"

Qi Hong answered this question with a look of embarrassment, "using methyl ethyl ketone inhibitors is the most common method today."

Huang Haitao waved his hand and said, "you can use it right away. Is there no such inhibitor in this hospital? That's easy. I'll think of a way. "

Tiejun hastily added, "Mr. Huang, it's not that we don't have laboratories here, but there are too many, there are as many as 43 kinds. Each gene segment is different, and the consequences are different. Each will cause different side effects, as long as the wrong use, the patient's condition will immediately aggravate, or even die. "

Huang Haitao tilted his head and asked strangely“ Then we can find the right antidote by screening all of them

"In theory, the gene mutation caused by each patient is different, that is, the gene mutation of Mr. Huang and that of Chen Qun may be totally different types. In other words, every patient needs to do more than 40 trials. If the target is not in these 43 types, we have to continue to synthesize new inhibitors to cope with new gene mutations. "

Qi Hong explained in a hurry beside, let genetics is not the strength of the difficult little expert, understand the serious nature of the trouble.

"Show me the side effects of your 43 inhibitors."

Huang Haitao rubbed his head and looked at the tanks of medicinal zebrafish in front of him. I know that if each patient carries out 43 kinds of pathological tests at the same time, it is very likely that the results have not come out, and the patient will not be able to support and die early.

Qi Hong quickly passes the tablet to Huang Haitao. Huang Haitao looks at it and feels more and more headache. Most of the 43 drugs were written in English without translation, and only a few were translated. It seems that Qi Hong did the translation temporarily, and the grammar and sentence patterns are still a little messy, just barely understood.

Huang Haitao carefully scanned the 89 translated medicines and handed the tablet to Chen Qun, "Xiao Chen, you think if you choose one of these 43 medicines, which one is the most suitable one."

Chen Qun glanced at it and then used the time pause skill to enter the system space again to see what the gene mutation results of the system analysis actually gave us?

As soon as we entered the system space, a structural formula with more than 1300 genomes appeared on the large screen, with the names of three corresponding drugs given next to it.

However, what reassures Chen Qun most is that this system is taking the first patient as a sample to extract the immune antibodies in his body. The molecular formula has resolved more than ten groups of structural molecules.

Sure enough, target drugs are the king's way. Otherwise, one patient can analyze them once, and with modern technology, they can't reach the level of hundreds of patients to analyze them separately, and then the right medicine can be applied to the case.

In the twinkling of an eye, he retreated from the space system and pointed to the first drug on the tablet.

"My foundation is even worse than that of Mr. Huang. If it's my choice. Then I'll choose the first drug, selumetinib. After all, it has the least side effects. What's more, this is a clinical trial drug that has been translated into Chinese, which shows that it has the widest applicability and can be effective in most cases. "Sometimes the right medicine is so simple, it is very likely that the first medicine to think of is the effective medicine to treat the disease. Of course, Chen Qun will not reveal the truth of his cheating, so he has to make up and make up as usual.

Huang Haitao had no doubt about Chen Qun's luck and immediately waved his hand,

"Well, Zhou Lin and Ouyang Yang, you two, used to use selumetinib in the intensive care unit first for patient No. 0, and also for several other critically ill patients who did not respond to specific drugs, but the dose was halved. You continue to carry out the experiment. Qi Hong and Chen Qunxian, together with me, report the progress to President Liu. "

The Iron Army, who was observing under the microscope, suddenly said, "cross sl-327 off the drug list, and I see two, no, three tumors on the zebrafish."

Chen Qun looked at dozens of happy zebrafish swimming in a large water tank in the distance, and asked in surprise.

"Are these samples or test products for injection?"

"No, it's a serum antibody test sample from a mild patient. It's two hours before we know the result. We not only injected the patient's serum into zebrafish, but also injected the same serum into five mice, two rabbits and four pigeons to see if it has any effect. But now look at the symptoms, at least that cured patients serum has a good immune effect

Qi Hong answers Chen Qun's question beside her. It turns out that after two poisoned patients recover, all symptoms disappear. Knowing that their bodies produced antibodies to the radioactive element cesium, they immediately extracted their serum and injected it into zebrafish for pathological experiments. Of course, this is what she is good at, directing three boys to complete.