It is a long process from paper to material object, from equipment to application, and then to paper.

The high efficiency of shotgun method one at a time is always in contradiction with its lack of accuracy.

However, history has proved that the shotgun method is the ultimate winner, only some key points need to be overcome.

What is currently used in the academic circle and is also to be used in the human genome project is the clone by clone method, which is easy to remember in English. It's called clone by clone, one clone by one.

Shotgun method or shotgun method, is a shot out of a piece, and then pull back the body assembly mode.

If we make a metaphor, the current use of rifles in the academic circle is one rifle at a time, and the effect is very good.

The shotgun method is more like a machine gun. Once you sweep a large area, there will be some fish who miss the net from time to time, but it doesn't matter. If you sweep more, the coverage rate should be satisfactory.

In fact, in the face of a dense enemy, machine guns are easy to use.

Just before that, there were too many problems faced by machine guns. How can they continue to provide orders? If the problem of fever is solved? How to solve the logistics problem? How to solve the weight problem of gun body?

Yang Rui's paper today is a problem-solving paper.

In terms of style, the style of such an article is actually not high. At best, it is a tactical article, not to mention a strategic article from a strategic perspective. It is weak in comparison with the tactical explanation articles, such as the implementation of the human genome project.

However, style is more like a chain of disdain, just a universal concept.

The real judge of the value of an article depends on what problems it solves. After all, a paper aims to solve problems. Strategic articles solve strategic problems. Tactical articles sometimes solve problems that show future breakthroughs, such as steam engines, such as internal combustion engines, such as electric motors, such as airplanes, missiles, satellites, such as machine guns Router and PCR.

"By using a large number of computers, we can solve the last bottleneck of bird shooting, if we complete the puzzle. Of course, the speed and cost of today's computers are relatively problematic, but in this regard, I believe that the development of the computer industry itself will give us a lot of help... "Yang Rui simply read papers, not too much voice and emotion, let alone emotional recitation.

It's not the way of scientists to use emotional resonance to attract scientists' attention.

For Yang Rui, this is just another routine project, but for scholars in the field, it is another earth shaking change.

Yang Rui's thinking is very logical, which is evaluated from the perspective of praise.

In fact, Yang Rui's thinking is very rough.

He just has an idea: I think it's the closest to demolish the house from the middle road.

Then, one tower after another will be demolished. No matter whether there are soldiers or heroes of the enemy in the middle, they will be killed.

Other scholars give up when they encounter a tower that is difficult to tear down, and give way when the enemy comes.

Yang Rui does not consider these at all, direct hard solution: do!

Of course, rookies also have fierce, the most powerful is that Yang Rui all the way hard solution in the past, unexpectedly solved the answer.

After reading a paper, the whole room was silent.

It's a surprising conclusion.

In other words, the conclusion is too unexpected.

While we are still ridiculing the weakness of the shotgun method, Yang Rui has proved the superiority of the shotgun method in the human genome project with irrefutable figures.

So, is the paper of Nobel Prize winner Yang Rui true?

Most people will not doubt Yang Rui now.

Doubt is the most unreasonable.

Only in this way, the change is too big to accept.

If the paper is true, many biological laboratories, previously constructed gene detection mode, will be changed.

"Professor Yang, you should have published your paper earlier."

"In fact, you don't need to save such articles. If you send them earlier, you don't need to scare everyone out of their research."

"Yes, I have to change my direction. It's too hard."

Scholars talk about it one after another. Those who stand up to ask questions are not so much doubters as those who do not accept reality.

Rough problem-solving ideas a little good, its answer is really ah, there are not so many detours to around.If the human body is compared to a square, the human genome project is to know the location and identity of everyone in the square.

How does cloning work: it asks these people one by one.

What about Yang Rui's shotgun technique? He is a sudden hit in the past, shooting a square of broken meat, and then send the younger brother to spell broken meat, and then recognize the face.

Do you have any questions about this way of thinking?

The bodies are all in the original position. If you don't believe it, go and verify it.

Yang Rui answered one by one, skillfully like an old butcher. In a few words, he took apart a pig and couldn't see its shape.

Scholars find familiar parts of the certification, no doubt after confirmation, the butcher's work is completed.

We each buy meat home, the stew of the stew, the stew of the stew, the sweet and sour of the sweet and sour, the world is harmonious, a great harmony.

As for the skinny pigs sold by the butcher next door, no one cares. No wonder others.

Who let you choose the pig is not good.

The routine meeting of human genome project, which Yang Rui joined, ended in silence.

What Yang Rui brings back is not only the specific work arrangement, but also the praise and resentment of the academic circles.

Of course, for the ion channel Laboratory of Peking University, Huarui laboratory, or Peking University itself, praise and resentment are excellent things.

In such an atmosphere, even the media have become a lot more clever, just reporting the progress of some human genome projects.

Yang Rui rarely stayed quiet for two days.

When it was time to turn around, only a few media came to interview again.

Perhaps with a few days to buffer, the problems of the media are more directional.

Besides the routine personal gossip and industry gossip, a reporter suddenly attacked and said, "Professor Yang, in your speech, you said that using the shotgun method requires a large number of computers. Will your research in China be the same?"

"Of course." Yang Rui nodded.

The reporter secretly took out a knife: "can the Chinese government provide such scale of funds and equipment?"

"Well, I'm going to invest some of my own money for the start-up." Yang Rui said and explained: "I'm ready to invest in the Nobel Prize, especially the profits from sildenafil."

In fact, it's impossible to have so many, but at such a time, it's unnecessary to say so.

The reporter nodded, his face full of excitement.

We all know the amount of Nobel prize money, and the income of sildenafil is even more important.

In a flash, several reporters have made a number of article titles in their minds

Chinese scientists raise funds for scientific research

Chinese government's reduction of scientific research funds

Selling off the property of Chinese Yang family

Father of cloned sheep in financial difficulties

Yang Rui doesn't care.

On the one hand, the total amount of money he has invested is not high. From the official launch of the human genome project to now, that is, less than $5 million has been invested, and the later budget of $5 million must not be spent.

On the other hand, the human genome project is not really without benefits. It just depends on whether he wants to take advantage of it or not. If necessary, Yang Rui is not a later supplement.

Of course, the most important thing is that Yang Rui has money now.

Not counting sildenafil's late earnings, he has more than $1 billion in cash. In terms of wealth, the value of drugs such as desferridone is estimated at US $1 billion, not to mention sildenafil. Companies such as Huarui are more valuable.

If we take a long-term view, Yang Rui's understanding of money has been greatly improved by his hundreds of courtyard houses in Beijing, his collections, and dozens of apartment buildings, as well as the pharmaceutical Valley and one million houses in Shanghai and Shenzhen.

Money can't buy me happiness, that's it.

Yang Rui didn't even bother to argue with the Ministry.

But, for the mass media, the story is too predictable.

Is it neuropathy or sensationalism to pay for basic research? Is it a mystery or is it true? Is it social retrogression or state inaction

When Yang Rui's plane landed and went to school after a day's rest, the discussion in the North Triangle was already full.

More students, spontaneously organized, found Yang Rui and vowed: "Professor Yang, if everyone uses their own money to do research, China's scientific research will really be over. We will go to petition the school leaders for you.""No, it's not necessary." Yang Rui's answer is very guilty. He would like to say that the school leaders and I are of one mind, but now Peking University also does not have tens of millions of dollars of spare money.

When Yang Rui's face was thin, the students said indignantly, "if you don't say it, let's say it. It's unreasonable that Nobel laureates can't do research because of money. Is China still short of such a little money? "

Without waiting for Yang Rui to open his mouth again, the leading students have turned their heads and run to the administration building.

Yang Rui watched the back of the students, only felt a little funny, but also felt a little moved.

It's impossible to get the ideal result when you report tens of millions of dollars to the school leaders. But it's something they risk to fight for.

"Give Professor Cai a call and say it." Yang Rui said to Xu Zhengping, and pulled the book, Geng Xin told two. He didn't call himself to avoid being asked.

On the contrary, Yang Rui simply went into the laboratory and closed the door to do the experiment, thinking that if he didn't show up, the discussion outside would gradually subside.