Chapter 1291

Nissen stooped, found two pieces of toilet paper from his buttock pocket, then took out the pen which was always at hand, and wrote a few words on it.

"Drug effects" and "primary cells" are written at the top by Nissen, followed by dynamic mass re measurement.

Nissen was not prepared to take notes today. He worked in Astra for 15 years. Before that, he was a visiting professor in several universities in Norway. He was a kind of person who came out to make money in the industry after he became famous.

Because of his familiarity with the field of basic biology, Nison scorns most biologists and will participate in today's lecture only because other people in the office are involved. As a Norwegian working in Sweden, Nissen doesn't want to be independent, whatever the reason.

Now, it seems, Nison thinks he's on the right track.

The only regret is that he didn't bring the right notebook.

He looked to the left and right. People on both sides were carrying notebooks and were looking down to take notes. Their pen speed was very fast and their handwriting was scribbled, but they almost wrote down what Yang Rui said.

Nissen was a little envious.

He felt that everyone was lucky today. Yang Rui, who was born in China, obviously did not pay enough attention to his knowledge, so that he said such an important thing for no reason.

The drug effect of human cells is a topic that pharmaceutical companies desperately want to study.

How the drug changes in the human body, or the so-called pharmacokinetics, do not know how many researchers died.

Who would have thought that a Chinese scholar should have studied it like this. What's more, it was made in the spare time of G protein coupled receptor.

Nissen believes Yang Rui's words. People who can hold up the banner of GPCR can be said to be the top figures in biology. However, how can we make research on drug effects easily?

Nisen wanted to say it was unbelievable, but listening to Yang Rui's open and detailed description, he didn't want to belittle him.

Any devaluation, at this time, should not be in the heart of researchers.

Nison wrote down two words on the toilet paper again, and then looked at the handwriting in front of him. He was a little annoyed.

He really didn't want to waste the opportunity he had in front of him.

"Hello, can I have two pieces of paper?" Nissen spoke with difficulty.

It's never easy for Swedes, Norwegians and Danes to ask for help.

Helping others, on the other hand, is an admirable quality. The researcher sitting next to Nison did not hesitate to tear off seven or eight pages from his notebook, handed them to Nison and asked, "is that enough?"

"Enough."

"All right."

The conversation was brief, but both were satisfied.

In Sweden, you can't be too active in helping others. First of all, you have to make sure that the other party is willing to accept the help. Otherwise, people who rush to work hard when they see others pushing their carts, even if they won't be reprimanded, will also cause complaints.

The researcher next to Nissen has long wanted to help him, but he can only tear the paper to Nissen after he takes the initiative to speak, so that Nissen doesn't just like painting on toilet paper.

Many people regard Swedish customs as a legacy of Viking culture, but the Swedes themselves don't care what others think.

They care more about achieving their goals.

For example, Yang Rui is explaining the "dynamic quality re measurement method", which makes many people feel closer to the target.

"Dynamic quality reset method, the optical signal is obtained. This signal is the sum of all signaling pathways activated by GPCR. Just so, we can't judge the response of cells to GPCR. Fortunately, I found another point Yang Rui's lecture is not vivid, but the logic is clear, and the researchers nodded to themselves.

This is the most popular lecture mode for scientific researchers. Dry goods are not boring, which is a bit like official document writing.

Researchers are very short of time. This time, it is also because of Yang Rui's fame that they are willing to attend the lecture. Naturally, they want to hear useful content.

Yang Rui is also very clear about this point. Occasionally selling a pass will not waste your time to guess. Instead, he said: "according to my observation, optical signals are different in essence according to different cells, because different cells express different pathways according to the stoichiometry of different signal pathway elements..."

Yang Rui gave a brief explanation, He stopped and said with a smile, "the earliest research I did on ion channels is actually slightly related to this aspect, so when I saw the problem of signal pathways, I immediately had an idea."Nisen and the researchers around him nodded, not that they appreciated Yang Rui's sharpness, but that they hoped Yang Rui would skip this topic and continue to talk.

Yang Rui did not go on talking about his research history, but he still took into account some ion channels.

Although a few years have passed, Yang Rui is still the world leader in the research of potassium ion channels.

This is also the characteristic of high-end scientific research. Unless people behind you continue to use corpses to pave the way for you, otherwise, the rugged mountain roads always hinder most people's climbing.

For industrial researchers, whether it is ion channel, light channel or G protein coupled receptor, it is a difficult problem.

Under normal circumstances, they will not go after these complicated problems. There is a lot of knowledge in the world, and no one can master it all.

However, Yang Rui's topic is too tempting.

If the dynamic quality re measurement method can play a role, or not all of it can play a role, as long as it can have the 60% or 70% utility described by Yang Rui, the whole pharmaceutical industry will be changed.

In the future, all new drug research involving GPCR, according to Yang Rui, more than 50% of future new drug research can be based on this method to screen active substances.

Think about it. If an active substance is found, and then to carry out various researches, and then to carry out various clinical tests, it will cost at least tens of millions of dollars. If it is carried out in clinical phase III, it will cost hundreds of millions of dollars.

Yang Rui's dynamic quality re measurement method can not shorten this stage, but it has an advantage that it can have a deeper understanding of an active substance and screen out some unqualified active substances.

It's still only part of it. But if you think about it, every active substance here used to be screened with tens of millions of dollars, the value of this part is too great.

As long as the researchers present think of this, no one is not serious.

In fact, this method can be used not only for original drugs, but also for generic drugs, which are ten times as many as 100 times as many.

Generic drugs are not copied directly. You have to follow several steps. If you simplify, you will have to spend millions of dollars.

If the total cost is calculated, the method proposed by Yang Rui now can reduce the total cost more.

A group of people looked at Yang Rui with admiration.

Everyone thinks it's amazing that Yang Rui can come up with this routine, but it's silly to just say it.

"Chinese researchers are pure." Nissen had a sudden desire to talk, so he said it in Swedish.