Jing Yulan brought the news that Tokyo University, Kyoto University and Waseda University participated in the research of GPCR, but Yang Rui was not surprised.

This made Jing Yulan anxious and said: "these three schools are very powerful. Their funds and talents are better than those of Peking University. Together, you have to be more careful."

What she said is euphemistic. At the level of 86, Dongda is a world-class school. Peking University has no ranking at all. It is inferior to Cairo University in Egypt or covenius University in Hungary.

However, this problem of external cognition has never been considered by Yang Rui.

He is a tiny smile, embrace Jing language orchid way: "I know, I also didn't prepare and east big they compare."

"They want to rob you of your honor and achievements." Jing Yulan warned Yang Rui as tactfully as possible. She works in school and knows a lot about scientific research. It's also a field. If the achievements in this field will get important awards, will the winners be the ones who contribute the most?

Of course not.

Even with the public's "public" thinking, the person who gets the most honor may be the one who makes the final result, which is exactly what the so-called result is.

But shouldn't the contributions of those who provide seeds, trees, cuttings and maintenance be more important than those who pick fruits?

However, this kind of thing, even in the scientific research field, is not clear. If all kinds of interest factors and political disputes are added, it is even more difficult to say.

There are three places for a Nobel Prize. It would be the most perfect situation if it is shared by those who provide seeds, those who plant and maintain trees, and those who pick fruits. However, in the history of Nobel Prize, the probability of such perfection is very small. The most common situation is that the last person who picks fruits gets two places, those who provide seeds, those who plant and maintain trees, Choose one and give it.

Take the field of G-protein coupled receptor as an example, those who make conformations are equivalent to providing seeds, and they are already eligible for the Nobel Prize. However, if Yang Rui fails to make achievements in the next two stages of crystal structure and three-dimensional structure, he is likely to lose the chance to win the prize.

Yang Rui is not worried about this, said: "Matsushima Heng came, I knew his plan, you can rest assured, Dongda again powerful, or a step slower than us, they want to make crystal structure, not I boast, they are wishful thinking."

Jing Yulan was said to laugh, Jiao said: "in the end is not boasting."

With soft words in his ears, Yang Rui felt that his heart had become crisp. He spoke in a relaxed way in later generations: "give me a little confidence."

Jing Yulan pouted and said, "Dongda is so famous... By the way, isn't there a professor graduated from Dongda in your school? Can you ask him about the situation? "

"What's the use of asking about the situation?" Yang Rui said a word, immediately wake up, good way: "also, I go to ask to see again."

Now he wants to appease Jing Yulan. After all, he can't say that I'm not afraid of Dongda. Given the current situation in China, no one believes that.

"You must be careful. The three universities are supported by consortia. They are more fierce than our subordinate universities." Jing Yulan reminds Yang Rui as much as possible.

Yang Rui just made a strong promise. In fact, he faced not only three Japanese universities, but also a large number of universities in the world interested in participating in the field of GPCR, especially some universities in the third world countries. Inspired by Yang Rui, he could not help but make some mistakes.

And those who are more famous than Tokyo University, such as the famous four brothers of Harvard, Oxford, Yale and Cambridge, also need people to do scientific research in this field. It's just their own strength.

This is also the fact that Yang Rui's strength is not enough, so that everyone thinks it is profitable. If the top laboratories are so far ahead, most of the large and medium-sized laboratories have to quit. It's like in the 100 meter race, bolt has started to run 10 meters away, and it's not so meaningful to spend a lot of money to participate in the race.

But if we change into Jin sipang on the track, he is 20 meters ahead, and some people still think he can take advantage of it.

Back in the laboratory, Yang Rui simply reported that three Japanese universities might be involved. The researchers did not look surprised.

Xu Zhengping is also calm way: "the Japanese is like this, can talk to you when the performance is very polite, back can't come according to his request, the knife without saying a word."

"There's no guarantee that they won't hand over the knife after the negotiation." Yang Rui said: "behind Dongda is Mitsui consortium. According to Matsushima Heng, he has at least 20 million US dollars. If more, it is possible to increase it to 30 million. The situation of Kyoto University and Waseda University is not clear, but they also have the support of consortia behind them. I estimate that the start-up funds of the two universities must be more than 10 million US dollars. If not, they will not be able to add in. "Yang Rui's ion channel laboratory has spent US $6 million in start-up funds. If Japan's laboratory wants to carry out research of this scale, it will not be meaningful to participate without US $10 million.

"It doesn't matter if there are 20 million, 30 million and 10 million for others." Fan Zhenlong gave out a hearty laugh, which was echoed in the laboratory.

Several researchers chatted more easily.

Yang Rui frowned slightly.

The morale of the ion channel laboratory is commendable. However, fan Zhenlong's words have brought a relaxed spirit and a strong appeal. It's like a person with low self-esteem who suddenly gets unexpected success and becomes too proud.

After thinking about it, Yang Rui looked at the table and said, "ladies and gentlemen, I'll say a few words."

There was a moment of silence in the laboratory.

"As fan Zhenlong said just now, there is a 23 million laboratory participating in the competition. It seems that we can not care about the 10 million dollar laboratory, just like our opponent has only one laboratory." Yang Rui looked around, pointed to his brain and said, "what do you think is the purpose of the $10 million laboratory to participate in the competition? Is it to lose? "

Everyone's smile gradually converged.

Yang Rui said: "under what circumstances did we participate in this competition, other laboratories will have similar criteria. To put it more clearly, there are no three or three people who dare not go to Liangshan. Nowadays, those who dare to join in the competition of scientific research are either rich in funds, talents, accumulation or unique skills. No one is stupid. No one dares to throw tens of millions of dollars into the water and listen to the sound. "

"Director Yang is right. We can't underestimate the enemy." Xu Zhengping knows what Yang Rui wants to express.

"But, after all, what else can they do?" A young research dog called out on the spot.

"There are many means." Yang Rui said: "let me give you a simple example. Suppose I am the director of the laboratory of Kyoto University. Now I know that the R & D Progress of the ion channel Laboratory of Peking University is the fastest, the capital and talent reserves of Dongda are the strongest, and Kyoto University has not accumulated enough technology. What should I do? I'm pre researching the next stage of the project. "

"Boom" in the laboratory, everyone seems to have something to say.

"It's too dangerous for them to dare to do it."

"Who knows when the second stage will be completed? Their pre research will be controlled by others."

"This is a gamble of 10 million dollars. If we find that there is a dead end in front of us, isn't the research behind meaningless?"

Among the questions, Yang Rui remained motionless. After a while, when the people were quiet, he said, "how long do you think we can finish the second stage of the study?"

No one spoke because no one could make a real decision.

Yang Rui didn't know. He just shrugged his shoulders and said, "at least we believe that we can complete the second stage of the research in a short time. That's why we invested so much, right? Is it difficult for the other party to make such a judgment? "

Looking at the people at the bottom, Yang Rui said again: "we are now focusing on the crystal structure of GPCR. Our enemy may be Matsushima Heng laboratory or the laboratory of the University of California. Our current advantage is that we have the first mover advantage, and the enemy has more abundant resources and manpower. In terms of resources and manpower, the laboratories that are not superior to us may skip the study of crystal structure and go straight to the ultimate goal of high-resolution three-dimensional structure. Then, assuming that we can win in the second stage, we may face other laboratories that have the first mover advantage. Therefore, we should not take the laboratories participating in the competition lightly. "

The laboratory became silent.

Yang Rui actually proposed a possibility that it would not be easy to skip the second stage and do the third stage R & D directly. Otherwise, there would have been laboratories doing this for a long time.

However, this is indeed a feasible way of thinking, and in the scientific research world, researchers' brain holes should not be underestimated.

Foreigners have no idioms, and they also have intelligence. Especially after Yang Rui completed the conformation of GPCR with great speed, more people may do so.

Both the "one pot" pretreatment method and the academic help brought by the clear conformation itself mean that the research of GPCR has been accelerated.

The air filled with relaxed feelings accumulated in the laboratory for many days was swept away by Yang Rui in a few minutes.

"Director Xu, you have people make a form in the laboratory." Yang Rui pointed to the white wall behind him and said, "now we need to arrange special personnel to track the trend of foreign laboratories at any time, and calculate the progress of other laboratories. En... Wu Qi, you can do this."……