"We now know that the structure of GPCR is composed of seven α The transmembrane structure composed of helix is not only so, but also part of its receptor contains extracellular N-terminal or intracellular C-terminal structure. This makes the structure of GPCR extremely complex

Yang Rui, holding the microphone, tells his opinion slowly.

At the bottom of the podium, there are close to 300 scholars and corresponding academic media.

This was originally just a project application meeting for the 863 plan. Somehow, the scale of the meeting increased from nine judges to nearly 300.

In fact, Yang Rui knows what's going on. This is a project application for G protein coupled receptor. If scholars in related fields are not curious, then the Chinese academic circle will collapse.

If you want to give a metaphor that is in line with the public's habits, in China in 1986, to apply for the project of "G protein coupled receptor" was like a project review meeting held by the space agency, which examined the project of "Sirius landing and colonization plan".

Of course, we all know that the landing and colonization of Sirius can not be accomplished overnight, or even impossible at all. However, as the applicant is a famous "Yang Rui", we are willing to listen to it even in order to know what the future will be like 300 years later.

As a matter of fact, it's hard to say who is more difficult than who is easier to thoroughly study what's going on with GPCR, which is related to the colonization outside the solar system.

Even if Yang Rui just took a small step, it was enough to make everyone listen.

However, Yang Rui does not just want to take a small step.

He took the microphone and looked at the crowd below. These may represent the highest level people in the field of protein in China. He said in a clear voice: "some structural biology studies have obtained structures with lower resolution. We can see the general direction of GPCR, but these structures are too rough, There are too many questions to explain. "

"I want to explain some of the problems." Yang Rui did not mean to be arrogant or humble at all. He said: "the problems I want to explain are as follows: before the 1980s, or earlier, before the 1960s, the Nobel Prize was often awarded to one or two people. However, with the development of science and technology and the increasing importance of the Nobel Prize, it is normal for three people to award the Nobel Prize.

For example, Yang Rui's current research on the structure and signal of GPCR should have been shared by American scientists Lefkowitz and kirbilka.

But that's 2012.

Since Yang Rui has chosen the mode of early research, he naturally doesn't want to play any more sharing mode.

In addition, the structure and signal are made together, so that people can roughly understand G protein coupled receptors.

If Yang Rui only does one of them, he still doesn't know when he will win the Nobel Prize.

G Protein coupled receptors are different from other fields, because this field is too difficult, so it is necessary to accumulate, but sometimes it depends on luck and inspiration.

Therefore, there is not a long distance between the 12 year Nobel Prize and the 02 year Nobel Prize, or even the 92 year Nobel Prize. At least for Yang Rui, it is not an insurmountable distance.

Of course, the chance of winning a prize is also very high.

It's normal for a normal Nobel Prize to wait ten, eight, or twenty years to win. Unfortunately, when people die and the lights go out, they haven't yet won the prize. The faster one is PCR, which usually takes a few years to get the chance.

However, the G protein coupled receptor is very powerful. In terms of the 12-year version, the achievements were made in 11 years and the awards were given in 12 years.

I can't help it. It's too Royal.

Of course, this is not to say that making G protein coupled receptor will definitely win the prize the next year. It can only be said that it will add another weight.

The Nobel Prize is the same as the costume.

You know that a boss will act like a God. The ultimate boss is a big probability, the big boss is a small probability, and the small boss is a chance. Therefore, the correct way to brush is not to brush an ultimate boss and look at his face, but to pile up a boss and pile up a corpse mountain. The God will fall into your hands after all.

Yang Rui is not very confident in luck, but he is quite confident in his ability to brush boss.

After a few more points, Yang Rui gave the microphone back to today's host, academician Zhu, who is also the project's recommender.

"Thank you, Comrade Yang Rui. Next, if you have any questions, please ask questions." Academician Zhu's voice is lazy, and his eyes are curious on a group of faces.

He wanted to know how many people really understood.The judges sat up straight, and several people made their voices almost at the same time.

"You first."

"Ask first."

"After you."

Several of them were humble again and again.

After that, Professor Qian, sitting in the middle of the judges, said, "Yang Rui, your plan looks good. Is it too grand?"

"It is indeed a grand plan, but I am confident that I can complete this plan through the ion channel Laboratory of Peking University, and prove that the ion channel laboratory is a world-class laboratory."

Wow.

The scholars in the stands are talking again.

Yang Rui just nodded slightly, looked at academician Zhu, then looked back and said: "the ion channel Laboratory of Peking University has raised 6 million US dollars and 2 million yuan of funds. This time, applying for 3 million yuan of total funds from the 863 program is also to enhance our strength..."

Yang Rui is very sharp, No more modesty.

Stand on the king's road and rush forward. Everyone will see you. No matter how timid you are, you can't hide.

Many people can't resist the attack of $6 million.

Professor Qian could not help but sit down quietly.

He will only insult himself if he asks questions now.

"Next, who else has a problem?" Academician Zhu asked softly.

The nine judges shook their heads.

"Vote now. Those who agree to pass the project and the amount applied, please raise their hands.

The nine claws were raised.

"Well, I announce that the first project of the national high tech research and development plan, the structure and signal of G protein coupled receptor, has been officially approved, and the person in charge is Yang Rui of Peking University..." academician Zhu's voice was not lost, and the applause rang out gently.

The louder, the louder, the louder.