Chapter 1078

At the moment of 1985, Yang Rui is quite confident in his own gender identification technology.

Sex identification of embryo is the highest threshold of embryo transfer.

Moreover, PCR was invented not long ago.

PCR It can be said that it is the strongest general technology in the field of biotechnology in recent years, and its impact on biology is no less than that of watt steam engine on industry.

Moreover, the effect of PCR is faster and stronger.

If it is exaggerating to say that every machinery factory during the industrial revolution had one or even more watt steam engines, it is not exaggerating that every modern biological laboratory had one or more PCR machines.

Of course, any technology has a process of development, the more general technology is.

In 1983, when PCR was just born, scholars were still at a loss. However, in 1985, many applications have been developed.

Using PCR for embryo identification is a technology that has just been developed for one year.

Before that, the method of cytogenetic analysis was still used in embryo identification, which was very complicated and the accuracy was not high. At least, it could not be compared with PCR technology with stable 95% accuracy.

According to the situation in China, the correct rate of sex identification by cytogenetic analysis is only 80% in many laboratories.

Sounds like good, 80 points on the test paper, it seems to be a good result.

However, 80% of the correct rate in practical application, can be said to be a disaster, almost difficult to use.

Suppose a farmer needs 100 heifer calves, and finally he gets 80 heifer calves and 20 bull calves. The trouble caused by this is not something good can solve - only the legendary calf meat can solve this problem.

Of course, restaurants like cheap and good calf meat, but farmers don't like it.

100 How about a million cows?

If you think about the needs of China animal husbandry Corporation, you can understand the seriousness of this problem.

For China animal husbandry Corporation, the only thing they need is cows, because their goal is to expand the population. As for bulls, the domestic market prospect is not very good. The most important thing is that they use US dollars for breeding, while sporadic meat sales can only get RMB.

In other words, an 80% accuracy rate is an additional 20% foreign exchange cost for China animal husbandry Corporation. This is, of course, an intolerable expense.

For ranchers, among the 1 million bulls that are going to sell meat, 200000 cows suddenly appear. They eat a lot. They are not fat and the meat is not beautiful. They can't be sold as calves. Finally, it's not as easy to grow naturally and sell heifers without sex identification and control.

Therefore, accuracy and accuracy are the key points of gender identification and control.

In the pre PCR era, animal husbandry was not very successful in gender identification and gender control. Most of the farmers and agricultural institutions would not adopt this cost-effective scheme.

In the post PCR era, the extremely high accuracy and accuracy bring revolutionary changes.

However, Yang Rui's paper is not prepared to consider this revolutionary change.

His paper focuses more on the application of PCR.

As the inventor of PCR, once again expanding the scope of PCR technology is originally a gimmick that journals like - academic journals also need gimmicks. For example, experiments with Einstein's brain cells attract more attention than experiments with anonymous brain cells.

Academic journal is a kind of journal after all, they also need attention and recognition of scholars.

Of course, this alone is not enough to be published in nature.

After all, it is the world's leading famous journal, and the gimmick is the icing on the cake.

What Yang Rui is really confident about is the primer he designed.

Primer is the premise of PCR. If PCR is described as a computer, the primer is the application of the computer. To do different experiments, we need to design different applications. In the 21st century, there are general design templates for primers. The work is relatively simple, which can be compared to the operating system of a computer. However, in 1985, PCR technology, which was just born, is more like a complex mainframe. There is neither an operating system available nor an easy input and output method. Each research requires additional design and special applications.

At this time, the primer designed by Yang Rui is actually an excellent model.Yang Rui believes that many scholars would like to see the PCR primers he made himself.

Although it is far from perfect, there is nothing perfect about academic research.

On the other hand, Yang Rui sent his paper to darbeko and other scholars simultaneously, which is not only for further communication, but also for beating the drum.

Communication through letters is something that western scholars were familiar with hundreds of years ago. Some of Gauss's research was collected from his letters.

Before the popularity of e-mail, scholars from various countries basically maintained this mode of communication.

Anyway, for academic research, a few days or more delay time is nothing.

Darbeko and others are also happy to learn about Yang Rui's work. As far as the current development of biology is concerned, there are just a few key figures, and Yang Rui can barely be one of them. Naturally, everyone has the desire to understand him.

Generally speaking, it is not as easy for Yang Rui to publish in nature as it is in domestic journals, but it is not too difficult.

Even if Yang Rui doesn't know much about his influence, this paper can be regarded as an attempt.

Yang Rui waited quietly, and by the way, he continued to direct the genetic engineering laboratory to carry out systematic experiments - the first batch of 10 Simmental cattle were led into the backyard of the genetic engineering laboratory.

The makeshift barn is a bit crude, but Simmentals probably don't care.

Several experimenters are curious to look at these cattle. For those who are used to yellow cattle, the strong Simmental cattle are really much bigger and stronger. In volume, it's a bit like the gap between Chinese garden dog and erha.

Sun Zhengchu and Prince ang quickly did physical examination for 10 cows and recorded the data.

Both of them are traditional geneticists who solve physiological problems for animals all the year round.

The new ten cows became the responsibility of sun Zhengchu and Wang Ziang.

Yang Rui doesn't have to manage any more. He doesn't know how to raise cattle or take care of their happy life. In fact, he doesn't have to do this.

Now that all the points have been broken, all we need is to do it again in the same order as before.