Ion channels, as the name suggests, are channels for ions to enter and leave the cell membrane.

The cell membrane is the protective layer of the cell.

The material that can enter and leave the cell membrane is the material that has the most ability to act on the cell.

Because of this, ion channels, as drug targets, are the most important link in the research of new drugs.

Since the 1960s, ion channels have been the focus of pharmaceutical companies' research, and they are also a few basic sciences that they will do research. The process from target to new drug is very complicated. There are at least two or three big steps, which takes at least ten years. However, pharmaceutical companies still spend money here because the research on ion channels is too important.

Any pharmaceutical company that wants to launch star drugs earlier than its competitors will have to pay a lot of effort on ion channel related research. And the famous heart medicine β Receptor blockers, is the leader of ion channel research. There are countless blockbusters born from this, including timolol, indolol, pralol, oxoprolol, metoprolol, atenolol, esmolol, carvedilol and bisoprolol, which are only used for heart disease

Therefore, to be an ion channel scholar is also an expert in physiology.

The full name of the Nobel Prize in biology is the prize in biology and physiology, which is the same reason.

It is difficult to distinguish biology from physiology or medicine in both academic and common sense.

Only early naturalists, that is, biologists in the Darwinian era, had a slightly different name. But in modern times, understanding animals and plants is only a basic skill. In the final analysis, zoologists, botanists and microbiologists have to study cells and even genes, Because it's an easier way to study and a faster way to understand and analyze biology.

Yang Rui sits in the ion channel Laboratory of Peking University. If he doesn't understand medicine, the audience may not think much about it. The academic community should first laugh.

Xu Wenshi originally wanted to argue with Yang Rui about his personal ability. After all, Yang Rui is just over 20 years old. Even if he has the ability to cross the border, he should not cross far.

He didn't expect that Yang Rui immediately raised the title of Peking University.

In fact, this kind of behavior is not good-looking. However, the gap between Yang Rui's age and Peking University's reputation only makes people feel the aura.

So far, Xu Wenshi is not qualified to have an independent laboratory, so he can only envy the envious circle and say: "the mainstream view of the pharmaceutical industry is in favor of the theory of antiarrhythmia. What I mean is that because you don't understand the pharmaceutical industry, you will resist the current mainstream view..."

"The mainstream view does not represent the right view." Yang Rui picked his eyebrows and said, "is it necessary to have a voting system for academic research? Who votes more, who is the truth? So what else do we do? "

"The research of mainstream scholars is valuable. You can't say that others are wrong without understanding them."

"Which mainstream scholar's research?"

"What?"

"You can say the names of three mainstream scholars to see if I understand their research. Can this prove that I'm not sensationalist?" Yang Rui is absolutely confident. If he talks about the unpopular theory, he may not know it, but he is full of mainstream views in various periods.

Domestic teachers and students often use it to cheat the review of influence factors. The standard writing method is how the research in history is, how the current research is, how the mainstream views are, how our views are

In the Internet age of information explosion, it is not too difficult to write such a review, Because the information is so easy to look up, do it faster, and you can finish a review in three days, most of which is still used for English writing.

But Xu Wenshi is not used to Yang Rui's way of speaking. This is a debate to be broadcast on TV. It's like a middle school student quarrel.

However, Xu Wenshi decided to seize the opportunity.

He thought for a moment and said, "Yamaguchi."

"TP te interval and safety evaluation of antiarrhythmic drugs, drug-induced QT syndrome patients study," Yang Rui said casually

“shah……”

Without saying that, Yang Rui said, "the concept of triad emphasizes the role of action potential morphology, trigonometry, drug reaction dependence, electrical instability and dispersion in predicting the market of Western women."

1

Put forward three names, instantly used up two.

Xu Wenshi's face turned brown again.“saint。” Academician Wang coughed and called out the third name instead of Xu Wenshi.

Yang Rui's eyes narrowed and said with a smile: "intracellular sodium and calcium exchange, intracellular calcium overload, arrhythmia, and heart failure models of human and dog... This is a free question for you."

Several people in the tense atmosphere of a Leng, are laughing out.

Academician Wang also slightly smile, said: "you do the work of potassium ion channel, more complex than these questions, ask three questions is useless, ask 30 is not necessarily useful."

Zhou Xiang, the host, almost looked at Yang Rui with star eyes. He pretended to look at Academician Wang and said, "so, Yang Rui won the debate just now?"

Academician Wang looked at Xu Wenshi and said with a smile, "in a debate, it's only when the opponent admits it."

Staring at by a member of the academic department, Xu Wenshi had to say obediently: "I really lost."

"Congratulations to member Yang Rui, let's go to the next city first." Zhou Xiang immediately clapped his hands and praised him, but he rolled his eyes.

Yang Rui just smiles and says, "who's next?"

Jiang Zhitong and di Hesong looked at each other, but they were not very happy.

Yang Rui is very powerful. If he loses face like Xu Wenshi, he will be ugly.

Although the coverage of Beijing TV station is not wide, Beijing alone accounts for 70% of China's academic elite, not to mention the large number of political figures. The purpose of scholars' fame is to fight for funds and power?

Jiang assimilation and dihesong do not want to be footnotes of bad news.

At this time, Jiang assimilation suddenly regretted that Yang Rui was young and handsome. Standing among several people, he seemed to stand out from the crowd. Even the host felt inclined to him. On the other hand, even if Jiang assimilation and others won the debate over Yang Rui, what would happen?

Yang Rui is only 20 years old, but he can't argue. What's so great about four middle-aged and elderly scholars?

In the case of not meeting each other, the idea is one thing, but after meeting and standing together, the feeling is different.

"Researcher Di, after you?" Jiang Tong pretended to be modest and pushed dihesong to the front desk.

Dihesong was also modest, and said: "director Jiang first, when you're finished, I'll find out what's missing."

"You'd better come."

"Please come."

Yang Rui looked at them, but he didn't care.

He really doesn't care much. His purpose is to explain his point, to stop the production of Jingxi general pharmaceutical factory, at least to reduce the number of victims.

Apart from that, things will not change much from the beginning.

Instead, the director, unable to see their humility, coughed and stood up and said, "researcher Di, you are the second guest. Otherwise, you can talk first."

The red light of the camera went out for a while, and di Hesong felt a little more relaxed, so he nodded.

"Bang bang"

The door of the studio was knocked.

"Look who it is." The director frowned a little.

Sun Xuan ran to open the door, but a long line of people came in.

"It's all there." At the beginning of the door was the director of the external liaison department. He laughed twice and said, "I think you've stopped, so knock on the door. Here are two foreign journalists who want to listen in to the debate. The director has already agreed. One more camera will not affect it."

The director thought to himself that the director agreed to it, which would affect me.

He nodded in annoyance and said, "put the number three seat. Just keep quiet."

"OK, no problem." The director of the external liaison department immediately called the foreigner behind him to set up a camera.

I saw two groups of four foreigners, one set up a camera, the other set up a thick tube camera, and then excitedly asked the translator to identify people.