Chapter 912

In front of Yang Rui is an application for a new drug to enter the market.

In the upper right corner of the document, the audit committee members are fan Yuanwei, song Hongxi and Yang Rui.

Yang Rui has met fan Yuanwei and song Hongxi, but he is not familiar with them. He can't even remember whether they are university system or research system. However, these are not important.

It is not uncommon for new drugs to apply for WTO entry. China is not the United States. In the FDA of the United States, the approval of any new drug or even any generic drug will bring about a chain rise in the shares of pharmaceutical companies. Any signing will mean the value of hundreds of millions of dollars. FDA of the United States passes about 40 kinds of new drugs every year, and several times more generic drugs, which will bring the attention of the media and industry every time.

However, China is a late developing country. There are countless mature drugs used abroad, waiting for the approval of the Chinese government. In addition, there are generic drugs of generic drugs and Chinese patent medicines. In the most year in China, 2000 or 3000 kinds of drugs have been approved into the market. Except for the relevant enterprises, other people don't care what the average seven or eight kinds of drugs approved every day are used for, Or is it really useful.

What shocked Yang Rui was the familiar and strange name of the drug: Tambocor.

Jingxi pharmaceutical factory also marked it with the translation Name: LV boding.

Yang Rui looked at it three times and searched for the information in his mind. Finally, he decided that this Tambocor was that Tambocor.

A lethal drug that could kill tens of thousands of people!

Compared with the famous drug disasters in history, such as the poison capsule incident in China, Tambocor is almost unknown. However, the industry is not unaware of this drug.

Because the number of deaths caused by the drug may be the highest in the world.

This is a drug for premature heart beat.

From the perspective of the 21st century, there is no need to treat premature heart beat. Ordinary people may have premature heart beat. As long as there is no more serious problem, premature heart beat needs no attention.

However, this view of the 21st century is derived from the lives of tens of thousands of people through drugs such as Tambocor.

In the 1970s, especially in the 1980s, the idea of treating premature heart beat became popular.

In fact, in this golden age of science, even ordinary people have a feeling that we can do everything - maybe only ordinary people think so, doctors and pharmaceutical companies use this idea to try to treat all the diseases they can think of.

Premature heart beat is one of them.

Maybe some people say that premature heart beat is premature heart beat. Since it has no effect, why should I take medicine? And long term medication.

However, ordinary people's ideas are always influenced by the academic circles, which may have delays, distortions and changes. However, when the academic circles have really reached a consensus, few ordinary people are not affected by this.

Patients are influenced by doctors, and doctors are influenced by medical experts, which is the operation rule of the medical world.

As early as the 1970s, the medical community came up with a theory that made pharmaceutical companies ecstatic: ventricular premature beat may in some way lead to fatal fibrillation and cardiac arrest, leading to sudden death.

Although there are such attributives as "may" and "certain", the theory of premature heart beat in the medical field is still in line with the expectation of pharmaceutical companies, and the view that premature heart beat may cause death is not obvious.

Since premature beat may cause death, it is natural to develop a drug to inhibit premature beat in order to avoid death or at least reduce the proportion of death.

tamboocor Therefore, it came into being and became a star drug in the 1980s.

Pharmaceutical companies hype this, and doctors prescribe millions of copies.

Patients have few choices.

Tambocor is able to stand out from an average of 30-40 new drugs a year and 300-400 new drugs a decade. Naturally, Tambocor has its value.

Its main value lies in: first, premature heart beat is a common disease (phenomenon); Second, to suppress premature heart beat requires long-term medication.

First, it means a large audience.

Second, it means taking medicine for a long time.

A kind of medicine for treating diseases is actually of no value to pharmaceutical companies and investors, just like antibiotics. Why don't pharmaceutical companies continue to develop antibiotics? Why do pharmaceutical companies still pretend to be invisible in the age of super bacteria? Because antibiotics only need to take a week, at most a few weeks, to solve the bacteria. Even if the antibiotics used to treat superbugs are extremely expensive, such as tens of thousands of dollars, or even hundreds of thousands of dollars, they still can't make pharmaceutical companies recover costs, let alone profits.The number of patients with super bacteria is very small, which is just contrary to the first point. There are only a few cases of super bacteria in the world every year, and at most dozens of cases. For pharmaceutical companies, the scale of testing is not enough.

And can't take medicine for a long time is the most disgusting place for pharmaceutical companies.

If you can't take medicine for a long time, it means that the profit is not stable and there is no stable profit. Why spend ten years and hundreds of millions of dollars to study a drug?

Serious heart disease is also a disease that pharmaceutical companies don't like.

Similar to antibiotics, patients with severe heart disease are usually not suitable for long-term medication, and the number of them, although many, can not be counted as many. Most importantly, they often die, so that you have to constantly develop new customers.

It's easy to suppress premature heart beats.

There are millions of premature heart beats in the United States, and if a census is conducted, there may be tens of millions.

What about the global scale? At least ten times the number of American patients.

If you think about this number, it's almost comparable to the scale of diabetes.

The $10 billion market seems to be beckoning to pharmaceutical companies.

tambocor How can we not become a star drug.

The new drug market application in front of Yang Rui is evidence of Tambocor as a star.

tambocor The company behind it is obviously trying to extend Tambocor to the whole world.

Although China's pharmaceutical consumption capacity can not be compared with that of the U.S. market, 3M is obviously not prepared to give up the Chinese market as a long-term drug.

Yang Rui picked up the application and read it carefully.

And his brow, also quietly wrinkled up.

Jingxi general pharmaceutical factory has prepared very well. At least for the pharmaceutical agents, their applications fully comply with the provisions of the state and the GMP Committee.

Of course, such an application can't pass the examination of a well-known agency like FDA, but the domestic requirements are much simpler.

After all, in China, only the Chinese patent medicines that have passed the application can be loaded into a truck every year. Tambocor has at least done animal toxicity tests. There are some problems in clinical double-blind experiments, but it has also done so.

To be reasonable, taking the application form made by Jingxi Pharmaceutical General Factory as an example, Yang Rui's signature is the most in line with the regulations.

This kind of drug, which has been on the market overseas, basically goes through the motions when it submits an application to the Ministry of health.

The Ministry of health will transfer the application to the GMP Committee, and the office of the Standing Committee of the committee will assign the application to the audit team composed of three members, which is also a passing act.

But Yang Rui can't go on this cross.

Yang Rui sighed heavily.

"Now, there's a lot of pressure." Yang Rui thought in his heart, but he made a decision long ago that he would not pass the application of Tambocor.

Although Chinese people are not as rich as Americans, there will be millions of people with premature heart beat problems that do not affect their lives, but with the size of China's population, even tens of thousands of people taking medicine may cause hundreds of deaths, affecting hundreds or even more patients and their families.

As time goes on, or whatever happens, it is not impossible for the number of people taking medicine to increase to 100000 or hundreds of thousands, so that thousands of people will be affected.

If it had nothing to do with Yang Rui, he would not go out of his way to do charity - Yang Rui never believed that charity could change the world, he believed that science could solve bigger problems than charity, and he was better at it.

However, this incident happened to Yang Rui.

Yang Rui will be in the hands of the application repeatedly read three times, after confirming that he did not miss, it will be carefully locked into the drawer.

Then he stood up, took two deep breaths, opened the door and walked to the office of the Standing Committee of the GMP Committee.

……