Chapter 203

"Professor Yu, can't CUHK synthesize coenzyme Q10 through solanesol?" Director Hai was holding the phone, sweating.

The voice of the phone is a little distorted, but it clearly says: "our institute has no special research in this field, but as far as I know, there is no precedent of industrialization of this technology in China. It seems that Beijing Institute of biological products has a similar project. You can inquire about it. "

"I called and they've given up the project." Director Hai pinches the phone and feels strange.

Yang Rui even made a project that Beijing Institute of biological products didn't do. If it wasn't for the precedent of Xijie factory, he would have met a liar.

But if it's not a liar, this technology is too powerful. No wonder Jericho easily agreed to reduce shares, and it didn't ask for technology transfer as it did last time.

It seems that they knew that the value of technology was too high, so they did not discuss the issue of technology transfer at all.

Maybe it's the hope that after the factory is put into operation, it will steal teachers from it?

Director Hai was amused by his idea, and then he felt proud. Foreigners stole teachers from China. Domestic magazines and newspapers like to write such stories, but only those who are in the professional field know how far the gap between China and foreign countries is.

A full 10 years' delay has brought about not only 10 years' backwardness, but also 20 or 30 years' backwardness. China's technology is still in the field of biotechnology. In other words, the peak of China's technology is still in the field of synthetic insulin.

However, the synthetic insulin in the 1960s was not rare until the 1980s, but in China, few people can replicate this experiment.

Professor Yu gave a natural "Oh" at the other end of the phone and said with a smile, "it's a pity to give up. It's not strange. In the past two years, too many projects have been cut down, and coenzyme Q10 is not an important drug related to the national economy and people's livelihood. "

"Well, if the University of science and technology or Beijing Institute of biological products restart the project, how long will it take to see the results?"

"Our school will not do this project." Professor Yu said with a smile: "our current goal is to track the latest international basic research, such as biological macromolecules, stem cells, gene functional groups, etc. the production of coenzyme Q10 is applied. Even if there is national funding, it is not necessarily able to draw out manpower."

"Then Beijing Institute of biological products will restart the project. How long do you think it can be done?"

"It's hard to say."

"Professor Yu, if we are so familiar, you can analyze it and I will know how to make a decision." Director Hai said that although he was in charge of the sales of raw materials and refined chemicals across the country, he was in charge of four departments with more than 20 people, and none of them could do research. Whenever he encountered this kind of thing, he always asked a familiar professor.

Professor Yu is also willing to maintain a mutually beneficial relationship with director Hai. After pondering for a moment, he said, "I can't do the analysis for others. I'll guess. If this technology is restarted, it's a bit of luck that we can work out the results."

"What do you say?"

"Twenty or thirty years of laboratory technology, why can't we do factory transformation? There are many reasons. The main one is that coenzyme Q10 has special properties and its intermediates are not stable enough. Therefore, laboratory technology can not be directly used in factories. Industrialized production is tantamount to opening up a new way to produce substance a through solanesol, and then convert it into substances B, C, D, and finally to coenzyme Q10, which is called ABCD, It has to be stable. Do you think it's easy? " Professor Yu is a bit of a teacher.

But director Hai listened very seriously and asked, "I don't know much about technology. I just want to ask, isn't that true for other factory production technologies?"

"Not all. Some laboratory technologies can be directly used in factories, because the routes it takes in the laboratory and the intermediate products it passes through are suitable for factories. Let me give you an example. Chemical synthesis is like going from one place to another. The intermediate product is the bridge to pass by. There are four intermediate products, namely four bridges. Laboratory technology is like walking. Any bridge can be used, including floating bridge, wooden bridge and stone bridge. Researchers don't demand it. When they meet wooden bridge, they use wooden bridge, and when they use stone bridge, they use stone bridge, You can use a floating bridge. Factory production is like trucks pulling goods. Its conditions are harsh. At least it has to be a stone bridge. If the scale of the factory is large, it has to be a railway bridge. Do you understand? "

"That is to say, some laboratory technologies are all above Shiqiao, coenzyme Q10 technologies are all wooden bridges and floating bridges?"

"That's what I mean, but it's more than that. If you think about it, even if the first three bridges are stone bridges and the fourth bridge is not, you still can't pass. You have to go back to the third bridge, or the second bridge, or even the first bridge, and start again. If you can't find the way of the whole stone bridge, the synthesis scheme will never work. The laboratory technology of semi chemical synthesis of coenzyme Q10 has appeared for a long time. It shows that many people have explored the way, but it is not yet available. It shows that it is very difficult. If you want to know how long it can be done, I think no one dares to guarantee it. "The sea director in the heart had to worry about, at the same time once again for Yang Rui's level tut tut said amazingly.

He doesn't know much about technology, but he is a knowledgeable person. If one technical success is luck, it's hard to say that the second time.

However, director Hai didn't see anything after all, so he tentatively asked: "Professor Yu, if I say that a student has made this technology, what do you think?"

"Did some students do it? Which school? "

"I haven't verified it yet." Director Hai told a little lie, and then said, "do you think it is possible for a person, a student, to solve this industrialized chemical synthesis route?"

The other end of the phone was silent for ten seconds before Professor Yu's voice continued: "if you have the right equipment, equipment, systematic training, knowledge reserve and luck, you can do it by yourself. Students are strong and weak, not to say that they can't do it, but it's not easy... Let me say more, if someone can complete this technology independently, whether it's students or farmers, domestic research institutes should be able to arrange it openly.

The director of the sea had a worry in his heart and said, "I see. If the technology is proved to be true, would you like to have a look?"

Jerichon reduced its stake from 50% to 45%, not simply by 5%, but by giving up control. If Yang Rui and Sinopharm cooperate in foreign trade, they can decide the direction of the new joint venture factory.

Director Hai thinks that if Yang Rui is brought into the system and a certain research institute, the control of foreign trade of national medicine will be greatly enhanced.

This idea was considered by director Hai as early as the Xijie factory period, but now it is only strengthened.

He felt that with Professor Yu's help, he would speak better in both the Institute and Yang Rui.

Professor Yu was also curious about what he said, and said: "you have confirmed the technology. I must have a look. If possible, you can come to the University of science and technology to demonstrate it to our students and teachers. If it's not convenient, I'll make time to go there."

"We'll show you how to get you here." Director Hai laughs, and his words are very nice.

Just like Shen Pinghui, the director of Pingjiang Institute of biotechnology, will appear in front of provincial leaders as a professional authority of biology when necessary, China University of science and technology, which is now known as China's first university, is not lagging behind in the way of connecting academic circles with political circles, and Professor Yu's reputation in the circle is also quite high.

This kind of Big Bull character, and ordinary little Professor, are two levels, director Hai should also be careful.

After the phone call with Professor Yu, the director of Haichu waited for two days, and finally met Mr. Trapp, the chief representative of Jielikang, who came from Britain.

This time, he brought with him four men and more than ten kinds of instruments that can plug a jeep. How difficult it is to borrow instruments and equipment in China? Trapp learned from his last visit. This time, he doesn't want to experience it again.

Domestic research institutes, in many cases, do not give people direct use of the instrument, but let you list the requirements, and then send someone to operate, for fear that any mistake will damage the instrument.

However, Trapp is not used to this practice. This time, he simply installed a car of instruments from Hong Kong and donated them to several universities in China. This is also one of the various agreements of jerichon's investment in China.

Trapp sent the instrument to Xibao middle school, and then carried out the experiment of refining solanesol with Yang Rui.

In terms of some key steps, Yang Rui still refuses to disclose, but the number is less than last time. After all, he is also a person who has the money to register patents.

The experiment of refining solanesol was very smooth, and Trapp gave full evaluation, which gave great confidence to Jielikang and Guoyi foreign trade.

Director Hai and Frankie can't wait to sign the agreement with Yang Rui.

As Huarui pharmaceutical company is a Hong Kong company, the new joint venture factory has become a tripartite joint venture between China, Britain and Hong Kong.

However, in order to minimize the trouble of choosing the crude solanesol plant, the three parties did not have an external publicity agreement, but let the director of Haichang negotiate with each enterprise first.

Although Sinopharm foreign trade also has its own technical department, what they do is mainly foreign trade. It is impossible for them to master the technology if they want to know the technology. Therefore, director Hai invited Yang Rui to contact with various enterprises separately.

The production of Solanesol by plant extraction method requires thousands of tons of raw materials even for crude solanesol. To supply a refined solanesol factory, there should be at least three crude solanesol factories, and more than five would be better.

All these investments need to be invested by Sinopharm foreign trade. Of course, profits from crude solanesol will also be shared by Sinopharm foreign trade and related enterprises.Since he earned money from the foreign trade of national medicine, director Hai paid special attention to the in-depth exchanges with various enterprises. In addition, he also sent people to Yunnan and other tobacco provinces to learn about the local tobacco production and marketing situation.

For Yang Rui, director Hai's attitude is also very kind.

First of all, Yang Rui has won a certain political and economic status. He is a Huarui pharmaceutical company. Although it is empty shell like a leather bag company, it has many patents in it. If it falls in any place in China, it will not be ignored. These days, it's not that you can't think of going to Hong Kong to register a company to be a Hong Kong funded enterprise, but that you can't afford foreign exchange to do such a thing.

Secondly, director Hai has become more and more aware of the difficulty of semi synthetic production of coenzyme Q10. This is something that even the Beijing Institute of biological products can't guarantee. Yang Rui has made it. Whether it's lucky or a genius, director Hai thinks it's powerful.

Thirdly, it is because director Hai really needs someone to help him judge the conditions for building a crude solanesol factory. In this respect, foreigners are not credible, while his staff are of average level. On the contrary, Yang Rui has become the best choice.

Although he can't give Yang Rui a high reward, director Hai tries his best to serve Yang ruishu comfortably. The first thing he does is to move Yang Rui from the front building to the back building of Pingjiang hotel.

At the same time, smart local enterprises seem to have noticed something.

……