Chapter 743

What academician Zhong saw could not be described in words. A problem that could not be solved in the world was suddenly solved at this time of the first day of the Chinese New Year?

At this moment,

academician Chu on the other end of the phone heard his colleague Lao Zhong's rapid breathing sound for a moment. He was a little confused and asked curiously, "Lao Zhong... What did you see? How do you feel shortness of breath? "

"I..."

"I can't believe what I saw." Academician Zhong said sincerely, "it's solved! Finally, I made a simple comparison between the two data reports, and the final result came to a conclusion... "

at this point, it suddenly stopped.

What academician Zhong wanted to say suddenly stuck in his throat. His expression changed from shock to panic. He seemed to see something that subverted his understanding.

"No!"

"No, no, no!" Academician Zhong's frightened face kept repeating a word. The hand controlling the mouse kept sliding the wheel. His eyes became a little confused at this moment. He found some contents that could not exist at all.

"What's the matter?"

"What's going on?" Academician Chu was going crazy at this time, and he wanted to have wings on his back. Then he flew to academician Zhong to see what he saw. The God mysteriously lifted people's appetite.

"Professor Xu mang... He... In the new CRISPR CAS gene editing system, he replaced the original cas9 with another RNA directed nuclease." Academician Zhong said in surprise, "it's incredible... It's amazing!"

Academician Chu:???

The more you can't see, the more you want to have it.

Academician Chu is going crazy. Listening to the constant exclamations of his colleagues, he is nibbling away at his curiosity, and he is about to collapse at last.

"My God!"

"He not only upgraded CRISPR CAS gene editing system, but also solved a problem that was... Troubling to all biologists in the world." Academician Zhong said in a hurry: "he redesigned c2c1 nuclease, and now... C2c1 nuclease has been fully adapted to the vast majority of organisms!"

All of a sudden, academician Chu has completely collapsed. If the successful upgrading of CRISPR CAS gene editing system is only the beginning, then the redesign of c2c1 nuclease is the last straw to crush the camel.

C2c1 nuclease is thermophilic, which is impossible to develop into a gene editing tool. Moreover, the key point is that the original c2c1 nuclease will cut the non target single strand in double stranded DNA. The lower the temperature, the more errors, resulting in low editing efficiency.

This problem is the problem of the whole world. Many teams have tried hard, but they have failed... However, Professor Xu mang has successfully broken this dilemma?

Is this...

is this killing two birds with one stone?

"Old clock!"

"Send me the data quickly!" Academician Chu couldn't wait to urge: "I was tickled by you. Quick, quick, quick, quick, quick, quick, quick, quick, quick, quick, quick, quick, quick, quick, quick, quick, quick, quick, quick, quick, quick, quick, quick, quick, quick, quick, quick, quick, quick, quick, quick, quick, quick, quick, quick, quick, quick, quick, quick, quick, quick, quick

"Cough!"

"This only describes the role of the redesigned c2c1 nuclease, but does not give a detailed report." Academician Zhong frowned and said solemnly, "just a moment... I need to call Professor Xu Mang and ask what the situation is."

As a result, academician Zhong hung up and called Xu Mang in a hurry.

"Hello?"

"Professor Xu... You redesigned the c2c1 nuclease. Is this true?" Academician Zhong asked nervously, "are there any relevant research reports? What's more, it needs to be verified by experiments. AI simulation alone is not enough to convince people. "

"Although it has not been verified by experiments, the results have been completely obtained from the research reports of c2c1 nuclease all over the world by using AI technology. C2c1 nuclease is not not not suitable for gene editing, but it is very suitable."

"In short..."

"the crispr-c2c1 gene editing system developed by me has higher sensitivity, which can realize sensitive DNA detection and single base discrimination at the same time." "With my gene editing system, we can quickly detect bacterial and viral infections, genotyping and SNP mutation detection in cells, blood, animals and plants," Xu said with a smile

"Wait a minute, I'll ask Xiao Zhang and Xiao Cai to help me with the experimental data." Xu mang said with a smile: "by the way, can academician Zhong apply for a patent?"

"..."

"yes!"

"You'll give us free." Academician Zhong said in a hurry: "by the way, call me immediately when you have the result.""Well!"

"I want to publish it in nature. Should it be ok?" Xu asked.

Academician Zhong said in a hurry: "absolutely can!"

After hanging up the phone,

academician Zhong sent all six materials to his old friend's email address. However, after only half an hour, he received a call from Lao Chu.

"This..."

"it's unbelievable!" Old Chu's words with surprise: "just a report on the redesign of c2c1 nuclease, if Xu mang can publish it, it will be more perfect!"

"This is just the beginning... A new gene editing system like this needs to accumulate experimental data and improve on the original basis. However, it is enough to prove Xu Mang's greatness to be able to put forward such a framework concept." Academician Zhong said with a bitter smile: "old Chu... Has to feel that the waves behind the Yangtze River push the waves ahead, and one wave is stronger than the other."

At the same time,

at the same time, Xiao Zhang and Xiao Cai are helpless, and they are caught back by Xu Mang, but this time they have no complaints. They are exposed to Xu Mang's latest research results about the redesigned c2c1 nuclease.

At this time,

at this time,

they are conducting relevant experiments for this new crispr-c2c1 gene editing system, and at the same time, they are processing c2c1 nuclease more carefully.

This process took two days. For Xu Mang, there was no feeling in the past two days, just sitting in the laboratory knocking melon seeds and sending wechat with Xiaoman. However, for Xiaozhang and Xiaocai, the two days' harvest was great.

As a new intern researcher in the Institute, he seldom gets access to such top-level research projects. However, Professor Xu can not care about his experience and let himself join the research and become a part of this research. This kindness can not be returned.

"Are you ready?"

"This speed is OK..." Xu mang said with a smile: "you go to have a rest... Or go outside also OK, research all I am in."

Not to mention,

at this time, the two men were exhausted. After saying hello to Xu Mang, they hurried back to their dormitory.

After checking the relevant research reports, Xu went to his office in silence, opened his computer and began to edit his paper. At the beginning, he wrote down the name of the paper crispr-c2c1 gene editing system.

...

London,

the headquarters of nature, a famous scientific magazine,

originally, it was a very ordinary day for the editors of nature. However, some people did not want to make this group of people live too easily. At this time, a paper about to shake the world was quietly coming to Peter's email address.

"Nature's top ten people of the year will be published in this order." Peter, editor in chief, said to one of his subordinates: "pay attention to the order before and after."

In the list submitted by editor in chief Peter, Xu mang was simply looked over. There was a trace of dissatisfaction between the editor in chief Peter's eyebrows, and said seriously: "it's not shocking enough... Although it can be put in the main journal, it can't be put on the cover. These three research reports have not excited me."

This middle-aged man is helpless. There are so many papers that can shock the whole world.

"Editor in chief Peter... The quality of recent papers is generally not high, maybe Valentine's Day is coming..." the middle-aged man said with a wry smile: "many young scientists also need a little bit of romance."

"..."

"it seems that this has nothing to do with Valentine's day, but it has simply come to a low point." Pete said with a smile: "wait a second... Anyway, there are still two days, maybe in these two days, we can receive the research report that shocked the world."

At this time,

Pete opened his email and saw the name of the first email crispr-c2c1 gene editing system.

"In other words, do you know what crispr-c2c1 gene editing system is?" Seeing the title of the email, Peter was stunned for a moment and asked curiously, "I remember... There is no crispr-c2c1 gene editing system in the world?"

"There should not be."

"Crispr-cas9 gene editing system is available, and it is very popular in biological field at present." Said the middle-aged man.

Pete frowned and opened the email subconsciously.

After just a few seconds,

Pete exclaimed in horror, "it's him!"

......

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