Chapter 735

Beijing,

Institute of Biochemistry and cell biology, Chinese Academy of Sciences.

An accident two months ago cast an indelible shadow here. Although there were no casualties, it caused irreparable economic losses. Although China has been recognized as the world leader in the field of crispr-cas9 gene editing, there are still serious defects in this technology.

How to make up for this defect has become a task to be completed by the Institute of Biochemistry and cell biology, Academy of Sciences. Although crispr-cas9 gene editing technology has become the most popular technology in life science due to its simple, efficient and diversified characteristics.

Especially in the gene therapy of human diseases, it is known as one of the most potential transformative innovations in modern human medicine. Behind the success is often accumulated by failure. The accident two months ago is the best illustration.

In a certain department,

silence is always enveloping in this office. More than a dozen top researchers in the industry are having a headache to upgrade crispr-cas9 gene editing technology. A whole month has passed without any harvest.

For the study of regularly spaced clusters of short palindrome repeats, many people present are elites, but how to upgrade it is difficult for everyone, including many doctors.

At first,

everyone's goal is very great, to establish a CRISPR system beyond the existence, but with continuous in-depth research, it is gradually found that the cruelty of reality has exceeded everyone's imagination, CRISPR system can not be surpassed at this stage, only fine optimization is carried out on the original basis.

However, the CRISPR system has developed from the 1990s to the present, and has been upgraded by numerous biological scientists to the extent that it can no longer be optimized. At present, CRISPR system has entered a bottleneck period. If you want to break through it, unless you have a new theory.

Just like physics, the span from classical physics to modern physics is hundreds of years. From modern physics to new physics, it is still an unknown number. However, biology has just experienced a great change. When will the next change start? Just like physics, it is an unknown number.

"Alas..."

"how difficult it is A doctor in the office sighed with helplessness: "the world knows that the main challenge in the standard CRISPR – cas9 system is to reduce the miss probability, but who can do it? Even if it does... It's like borrowing the shell of CRISPR – cas9 system, and the content inside is completely different. "

"What are you going to do?" "If this problem is not solved, we may be greatly reduced funding, after all, this matter leaves too much shadow."

For a while,

helplessness surged into the hearts of all the people present. This problem is not a little bit of a difficulty. Unless there is a genius like Xu Mang, you can't succeed.

Xu mang?

Many people think of what happened a few days ago. About the artificial intelligence for predicting the three-dimensional structure of proteins from the amino acid sequence, it may have unexpected results if Professor Xu mang develops a similar gene editing AI.

"Ah?"

"Do you think... If Professor Xu mang suddenly designs a gene editing AI one day, will there be a world-class biological transformation?" The doctor said curiously, "I think it can... At present, the protein structure has caused a huge response."

"Hard!"

"It's hard!"

"I think CRISPR system is already the most perfect existence and can not be surpassed in a short period of time." The middle-aged man said with a wry smile: "this idea is different... After all, Professor Xu mang is engaged in physics, and occasionally plays in other fields, but gene editing is... I don't think it is possible!"

On the occasion of public discussion on this matter, academician Zhong came in and said to all the people present: "cough, please be quiet, I will announce two things here."

As a result,

in the office, everyone looked at academician Zhong standing at the door with a trace of doubt.

"First of all, I won the right to use the artificial intelligence" xuman system "to predict the three-dimensional structure of proteins from amino acid sequences." "In the near future, systematic hunting will be carried out. In the future, everyone can use this technology to study the protein structure," Zhong said

"Second... Professor Xu has accepted my request to help us achieve a breakthrough in the field of gene editing." Professor Zhong said, "but... I hope you can't start to relax because of Professor Xu's joining. You should still do your best."

“？？？”

“？？？”

“？？？”

He... Did he really come?

Hearing academician Zhong's words, many people were surprised and surprised, but then there were doubts, not about Xu Mang, but about their own strength.It's very sad to say that we should rely on a physicist to save the field. Is this our own biology in vain?

"In order to mobilize your enthusiasm, er... Your whole team will confront Professor Xu mang to see who can take the lead in completing the innovative work in the field of gene editing." Academician Zhong said with a smile: "he has only one person, but you have about a dozen. Should there be no problem?"

No problem?

This is a big problem!

If it was before, everyone was full of confidence. How could a person fight against a team of about ten people, but now... I'm sorry, we can really fight! And not only against one team. Not long ago, Xu mang suppressed nine American AI teams with the strength of one person.

As we can imagine,

win more with less, not with one enemy against 100, nor with... It should be one man in charge of the pass, and no one can open a door. This is the routine operation of Professor Xu mang.

"Academician Zhong... You're kidding." The doctor said: "all kinds of deeds tell us that none of the competitors with Professor Xu mang have come to a good end. I guess we can't. this is not a confrontation of magnitude at all."

"Lost before the beginning?" Academician Zhong reluctantly said: "let's all cheer up. We can't rely on Professor Xu mang alone. What if he fails?"

As a result,

academician Zhong left and went to his office when he met a colleague, academician Chu, an expert in bioinformatics.

"Old clock?"

"I heard you went to Fuda university?" Old Chu asked curiously, "I remember you went yesterday? Why did I meet you here this morning? Don't you come back all night? "

Academician Zhong said with a wry smile: "yes... It's not to solve the matter two months ago. I hope to sum up the relevant experience according to a previous mistake, and then strive for a breakthrough in this field, but the breakthrough is so simple."

"So...

" did you find Professor Xu mang? " Old Chu said with a smile, "how is the situation? Did he promise? "

"Yes."

"At the same time, I got the right to use xuman system." Academician Zhong said, "by the way, Lao Chu... What do you think is the probability of Xu mang breaking through the existing framework in the field of gene editing?"

"I don't know."

"Don't ask me that question." Old Chu face dew bitter way: "his affair... I don't say at all."

"..."

academician Zhong said helplessly, "is it necessary to be so careful? The probability of "can" and "can't" is only 50%. It's so difficult to give an accurate explanation? "

"Not hard!"

"But if it's Xu Mang, it's hard... You should understand what I mean." Old Chu said seriously: "although he is engaged in physics, but he can do anything, and also very proficient in everything, which is totally unreasonable."

Academician Zhong chuckled: "tell your department, and help the Department of molecular biology complete the breakthrough task in the field of gene editing."

"Good!"

"Are you going to compete with Xu mang?" Lao Chu asked.

"Almost!"

"I want to see how far the researchers in our department are from Professor Xu." Academician Zhong said: "Professor Xu Mang's job is to do physics, and they graduated from biology. How much is the gap between the two? Don't you want to know?"

Old Chu opened his mouth and a stream of words was stuck in his throat.

To be honest...

not at all!

...

Magic capital,

Yang Xiaoman and Xu mang are walking in the street hand in hand. In fact, Xu mang doesn't want to come out in this cold day... And the cold in the south is not the same as that in the north. The North belongs to physical attack, while the South belongs to magic attack. With moisture, they will get wind dampness bone disease in their later years.

"Alas..."

"wife?"

"Are you not cold at all?" Xu mang asked cautiously, "I'm freezing stiff. I don't have to blow the heating at home. If I have a cold... Do you know how much loss to our country? The progress of a large research project is put on hold. Time is money

Yang Xiaoman: (~ ~ ~)

take a walk after a meal to increase the feelings between each other. Why so much nonsense?

I'm so angry!

"Will you die if you walk?" Yang Xiaoman said angrily, "aren't you studying gene editing? Can you edit your genes first? Lazy to death... "

after being educated by Xiaoman, Xu mang became more honest and stayed by her side in silence, carrying out cold wind activities.

At this time,

a pair of seemingly high school young lovers came to face.

"Auntie?"

"Auntie, wait a minute!" Suddenly, the girl ran to Yang Xiaoman and asked curiously, "Auntie, this dress is very nice. Is it warm to wear?"Ah...

Auntie?

Yang Xiaoman heard the little girl call himself aunt, suddenly brain short circuit, a face confused looking at her.

"Er..."

"it looks very warm. I want to buy one for my mother too!" The little girl studied Xiaoman's coat carefully and didn't seem to notice how terrible the expression of the owner was.

I...

Auntie?

Buy one for mom?

Yang Xiaoman has completely collapsed, as if he lost his nerve, couldn't feel his breath, and even suffocated the air...

suddenly, Xu mangyi hugged Yang Xiaoman and cried to the couple nervously: "run! Run! It's too late to run now, or you'll be sunk in the river

......

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